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Molecular identification and characterization of Acinetobacter species causing bacteremia

Research Project

Project/Area Number 24590675
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Laboratory medicine
Research InstitutionTohoku University

Principal Investigator

ENDO Shiro  東北大学, 大学病院, 講師 (40614491)

Co-Investigator(Kenkyū-buntansha) YANO Hisakazu  奈良県立医科大学, 医学部, 教授 (20374944)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
KeywordsAcinetobacter / Acinetobacter属菌 / Acinetobacter
Outline of Final Research Achievements

Acinetobacter baumannii is generally the most frequently isolated Acinetobacter species. According to a recent report from Norway, Acinetobacter nosocomialis was the most frequent isolate from blood cultures. Since the biochemical characteristics of different Acinetobacter spp. are almost identical, accurate identification at the species level is difficult with routine laboratory methods.There is the possibility of different clinical outcomes due to infection with different genospecies since a difference in antibiotic susceptibility between A. baumannii and non-A. baumannii has been reported.The isolates included A. soli (13, 27.1%), A. nosocomialis (12, 25%), A. baumannii (9, 18.8%), A. ursingii (8, 16.7%), A. pittii (3, 6.3%), A. genomic species "close to 13TU (1, 2.1%), A. junii (1, 2.1%) and A. guillouniae (1, 2.1%). Accordingly, our findings emphasize the importance of performing further epidemiological investigation of Acinetobacter species.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (3 results)

All 2014 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] High Frequency of Acinetobacter soli Among Acinetobacter Isolates Causing Bacteremia at a Japanese Tertiary Hospital2014

    • Author(s)
      Shiro Endo, Hisakazu Yano, Hajime Kanamori, Shinya Inomata, Tetsuji Aoyagi, Masumitsu Hatta, Yoshiaki Gu, Koichi Tokuda, Miho Kitagawa, Mitsuo Kaku
    • Journal Title

      Journal of Clinical Microbiology

      Volume: 52 Issue: 3 Pages: 911-915

    • DOI

      10.1128/jcm.03009-13

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Molecular epidemiology of Acinetobacter spp. causing bacteremia among community hospitals throughout Japan2014

    • Author(s)
      Shiro Endo, Hisakazu Yano, Hajime Kanamori, Shinya Inomata, Noriomi Ishibashi, Tetsuji Aoyagi, Masumitsu Hatta, Yoshiaki Gu, Koichi Tokuda, Miho Kitagawa, Mitsuo Kaku
    • Organizer
      24th European Society of Clinical Microbiology and Infectious Diseases
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2014-05-10 – 2014-05-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] 東北大学病院において臨床分離されたAcinetobacter spp.の菌種レベルにおける分離頻度

    • Author(s)
      遠藤史郎
    • Organizer
      第59回日本臨床検査医学会
    • Place of Presentation
      国立京都国際会館(京都)
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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