Microbiological and molecular epidemiological analyses of community-associated methicillin-resistant Staphylococcus aureus in Japan
| Project/Area Number |
24590676
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Nara Medical University (2014)
Tohoku University (2012-2013) |
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Principal Investigator |
YANO Hisakazu 奈良県立医科大学, 医学部, 教授 (20374944)
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| Co-Investigator(Kenkyū-buntansha) |
KUNISHIMA Hiroyuki 聖マリアンナ医科大学, 医学部, 准教授 (60339843)
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| Research Collaborator |
INOMATA Shinya
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | MRSA / CA-MRSA / 市中感染型MRSA |
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| Outline of Final Research Achievements |
In this study, the MRSA isolates were classified as CA-MRSA or hospital-associated (HA)-MRSA according to a clinical classification based on patient information and a molecular classification based on SCCmec typing. Additionally, we performed PFGE and MLST.
Of the 231 MRSA isolates, 28 and 78 were classified as CA-MRSA by the clinical and molecular classifications, respectively. The most frequently detected CA-MRSA clone was sequence type 5-SCCmec IV, which has not previously been reported in Japan. The numbers of detected CA-MRSA isolates differed between the molecular classification and the clinical classification and the CA-MRSA detection frequency and the presence of the ST5-SCCmec IV clone were distinctive features in Japan.
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Report
(4 results)
Research Products
(25 results)
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[Journal Article] A case of culture-negative endocarditis due to Streptococcus tigurinus2015
Author(s)
Kanamori H, Kakuta R, Yano H, Suzuki T, Gu Y, Oe C, Inomata S, Aoyagi T, Hatta M, Endo S, Tokuda K, Weber DJ, Nakamura Y, Saiki Y, Kaku M
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Journal Title
J Infect Chemother
Volume: 21
Issue: 2
Pages: 138-140
DOI
Related Report
Peer Reviewed
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[Journal Article] Prevalence of Smqnr and plasmid-mediated quinolone resistance determinants in clinical isolates of Stenotrophomonas maltophilia from Japan: novel variants of Smqnr2015
Author(s)
Kanamori H, Yano H, Tanouchi A, Kakuta R, Endo S, Ichimura S, Ogawa M, Shimojima M, Inomata S, Ozawa D, Aoyagi T, Weber DJ, Kaku M
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Journal Title
New Microbes New Infect
Volume: 3
Pages: 1-1
Related Report
Peer Reviewed
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[Journal Article] Impact of the 7-valent pneumococcal conjugate vaccine on acute otitis media in Japanese children: Emergence of serotype 15A multi-drug resistant Streptococcus pneumoniae in middle ear fluid isolates2015
Author(s)
Ozawa D, Yano H, Endo S, Hidaka H, Kakuta R, Okitsu N, Kanamori H, Ogawa M, Ichimura S, Shimojima M, Inomata S, Kaku M, and Katori Y
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Journal Title
Pediatr Infect Dis J
Volume: 34
Pages: 1-1
Related Report
Peer Reviewed
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[Journal Article] A case of severe acute otitis media caused by mucoid Streptococcus pyogenes in a previously healthy adult2014
Author(s)
Kakuta R, Yano H, Hidaka H, Miyazaki H, Irimada M, Oda K, Arai K, Ozawa D, Takahashi T, Kaku M, and Katori Y
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Journal Title
Tohoku J Exp Med
Volume: 232
Pages: 301-304
Related Report
Peer Reviewed / Open Access
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[Journal Article] Helicobacter cinaedi causing infected abdominal aortic aneurysm2014
Author(s)
Kakuta R, Yano H, Kanamori H, Shimizu T, Gu Y, Hatta M, Aoyagi T, Endo S, Inomata S, Oe C, Tokuda K, Ozawa D, Goto H, Katori Y, and Kaku M
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Journal Title
Emerg Infect Dis
Volume: 20
Issue: 11
Pages: 1942-1945
DOI
Related Report
Peer Reviewed
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