| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
Molecular epidemiological analysis was performed for antimicrobial resistant bacteria isolated in our hospital. Many carbapenem resistance gene positive enterobacteriaceae were isolated in the same period and the same ward. The result of the antimicrobial susceptibility testing of those isolate showed both carbapenem susceptible and resistant phenotypes. Those isolates showed the identical genotype on Pulsed-field gel electrophoresis, indicating the nosocomial spread of the strain.
Further, colonization of Metallo beta lactamase gene positive Multi drug resistant Pseudomonas aeruginosa strains with same genotype in our hospital was revealed.
The isolates of carbapenem resistant Acinetobacter baumannii were analyzed genetically. Multi Locus Sequence Typing revealed that the strain belonged Clonal Complex 92 as the global clone, and analysis of resistant gene identified the OXA23 beta lactamase gene.
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