| Project/Area Number |
24590718
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Kyushu University of Health and Welfare |
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Principal Investigator |
SATO Keizo 九州保健福祉大学, 薬学部, 教授 (00315293)
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| Co-Investigator(Kenkyū-buntansha) |
SHINYA Tomohiro 九州保健福祉大学, 薬学部薬学科, 助教 (60551299)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 酸化ストレス / フリーラジカル / ラジカル捕捉剤 / 抗ラジカル捕捉剤抗体 / 電子スピン共鳴 |
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| Outline of Final Research Achievements |
Oxidative Stress have important roles in various diseases such as diabetes, infectious disease, inflammatory disease, lung injury and aging. Threrfore, development of a correct and handy method of oxidative stress is desired. So we have developed the new radical measurement method which is stable and high sensitive by using an antibody of a radical trap agent. As a results, It could be confirmed that it can be gauged, a immunostain method, ELISA method and HPLC method. Consequently, I could think this method could contribute to a study of all fields as new oxidation stress measurement.
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