Study on catalysis of Asian dust to the secondary toxic chemicals in the atmosphere

• Project/Area Number: 24590769
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hygiene
• Research Institution: Kanazawa University (2013-2014); Hyogo Medical University (2012)
• Principal Investigator: TANG Ning 金沢大学, 薬学系, 助教 (90372490)
• Co-Investigator(Kenkyū-buntansha): SHIMA Masayuki 兵庫医科大学, 医学部, 教授 (40226197)
• Co-Investigator(Renkei-kenkyūsha): NAKATSUBO Ryohei 兵庫県環境研究センター (60463329) ; HIRAKI Takatosi 兵庫県環境研究センター (60446812) ; YODA Yoshiko 兵庫医科大学, 医学部, 助教 (80748434) ; HAYAKAWA Kazuichi 金沢大学, 薬学系, 教授 (40115267) ; TORIBA Akira 金沢大学, 薬学系, 准教授 (50313680) ; KAMEDA Takayuki 京都大学, エネルギー社会/環境科学専攻, 准教授 (50398426)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2014: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: アジアンダスト / 多環芳香族炭化水素 / 大気汚染 / 大気内反応 / 発がん性 / 変異原性 / 長距離輸送 / 有害化学物質 / 環境分析化学 / 化学工学 / 衛生学 / 環境分析

Outline of Final Research Achievements

Total four background Asian dust (Kosa) were collected at different desert regions of China. The specific surface area and the total pore volume of the Kosa collected at Huangtu plateau were larger than those at other regions (Taklimakan, Tengger and Horqin). But no significant difference in the average pore size was found among the four Kosas. The compositional differences of analyzed nine water-soluble ions and fifteen elements were observed among the four Kosas. We found that 2 - 4 rings polycyclic aromatic hydrocarbons (PAHs) can be adsorbed by the every Kosa in the conditions of presence or absence of light and reactive gases (NO2/SO2/O3) by using our exposure chamber. We also found that Kosa has catalysis to promote the degeneration reaction of PAHs to their nitro- and/or quinine-derivatives having strong toxicity.

Research Products

• [Journal Article] Polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarnons in atmospheric particles and soil at a traffic site in Hanoi, Vietnam. (2015)
  • Author(s): Pham, C. T., Tang, N., Toriba, A., Hayakawa, K.
  • Journal Title: Polycyclic Aromatic Compounds Volume: 印刷中 Issue: 5 Pages: 0-8
  • DOI: 10.1080/10406638.2014.903284
  • Peer Reviewed
• [Journal Article] Atmospheric Behaviors of Polycyclic Aromatic Hydrocarbons in East Asia (2014)
  • Author(s): Hayakawa, K., Tang, N., Kameda, T., Toriba, A.
  • Journal Title: Genes and Environment Volume: 36 Issue: 3 Pages: 152-159
  • DOI: 10.3123/jemsge.2014.016
  • NAID: 130004943665
  • ISSN: 1880-7046, 1880-7062
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Factors affecting atmospheric 1-, 2-nitropyrenes and 2-nitrofluoranthene in winter at Noto peninsula, a remote background site, Japan (2014)
  • Author(s): N. Tang, K. Sato, T. Tokuda, M. Tatematsu, H. Hama, C. Suematsu, T. Kameda, A. Toriba, K. Hayakawa
  • Journal Title: Chemosphere Volume: 107 Pages: 324-330
  • DOI: 10.1016/j.chemosphere.2013.12.077
  • NAID: 120005411652
  • Peer Reviewed / Open Access
• [Journal Article] Determination of Selected Nitropolycyclic Aromatic Hydrocarbons in Water Samples (2013)
  • Author(s): Chondo, Y., Ying, Li., Makino, F., Tang, N., Toriba, A., Kameda, T., Hayakawa, K
  • Journal Title: Chemical and Pharmaceutical Bulletin Volume: 61 Issue: 12 Pages: 1269-1274
  • DOI: 10.1248/cpb.c13-00547
  • NAID: 130003381791
  • ISSN: 0009-2363, 1347-5223
  • Peer Reviewed
• [Journal Article] Improvement of the Analytical Method for Quinoid Polycyclic Aromatic Hydrocarbons Using HPLC with In-line Reduction and Fluorescence Detection: Application to Soluble Organic Fraction of Airborne Particles (2013)
  • Author(s): T. Kameda et al.
  • Journal Title: BUNSEKI KAGAKU Volume: 62 Issue: 11 Pages: 979-984
  • DOI: 10.2116/bunsekikagaku.62.979
  • NAID: 10031196846
  • ISSN: 0525-1931
  • Peer Reviewed
• [Journal Article] Source contribution analysis of surface particulate polycyclic aromatichydrocarbon concentrations in Northeastern Asia by sourceereceptor relationships (2013)
  • Author(s): Inomata, Y., Kajino, M., Sato, K., Ohara, T., Kurokawa, J., Ueda, H., Tang, N., Hayakawa, K., Akimoto, H
  • Journal Title: Environ. Pollut Volume: 182 Pages: 324-334
  • DOI: 10.1016/j.envpol.2013.07.020
  • Peer Reviewed
• [Journal Article] Characterization and functionality of immidazolium ionic liquids modified magnetic nanoparticles (2013)
  • Author(s): Li, Y., Tang, N., Inagaki, F., Mukai, C., Hayakawa, K
  • Journal Title: J. Chem Volume: 861021 Issue: 1 Pages: 7-7
  • DOI: 10.1155/2013/861021
  • NAID: 120005302296
  • Peer Reviewed
• [Journal Article] Characteristics of Atmospheric Polycyclic Aromatic Hydrocarbons in Shenyang, Shanghai and Fuzhou, China (2013)
  • Author(s): 唐 寧, 伊崎陽彦, 徳田貴裕, 季 若男, 薫 麗君, 呉 慶, 周 志俊, 黄 蓉, 林振宇, 亀田貴之, 鳥羽 陽,島 正之, 早川和一
  • Journal Title: BUNSEKI KAGAKU Volume: 62 Issue: 4 Pages: 267-273
  • DOI: 10.2116/bunsekikagaku.62.267
  • NAID: 10031151799
  • ISSN: 0525-1931
  • Peer Reviewed
• [Journal Article] Evaluation of urinary metabolites of 1-nitropyrene as biomarkers for exposure to diesel exhaust in taxi drivers of Shenyang, China (2013)
  • Author(s): Miller-Schulze, JP., Paulsen, M., Kameda, T., Toriba, A., Tang, N., Tamura, K., Dong, L., Zhang, X., Hayakawa, K., Yost, MG., Simpson, CD
  • Journal Title: J. Expo Sci. Environ. Epidemiol Volume: 23(2) Issue: 2 Pages: 170-175
  • DOI: 10.1038/jes.2012.40
  • Peer Reviewed
• [Journal Article] Biological Effects of Polycyclic Aromatic Hydrocarbon Derivatives (2013)
  • Author(s): Bekki, K., Toriba, A., Tang, N., Kameda, T., Hayakawa, K.
  • Journal Title: Journal of UOEH Volume: 35 Issue: 1 Pages: 17-24
  • DOI: 10.7888/juoeh.35.17
  • NAID: 110009593197
  • ISSN: 0387-821X, 2187-2864
  • Peer Reviewed
• [Journal Article] How Do Transport and Metabolism Affect on the Biological Effects of Polycyclic Aromatic Hydrocarbons? (2012)
  • Author(s): Bekki, K., Toriba, A., Tang, N., Kameda, T., Takigami, H., Suzuki, G., Hayakawa, K.
  • Journal Title: YAKUGAKU ZASSHI Volume: 132 Issue: 3 Pages: 325-329
  • DOI: 10.1248/yakushi.132.325
  • NAID: 130001872028
  • ISSN: 0031-6903, 1347-5231
  • Year and Date: 2012-03-01
  • Peer Reviewed
• [Journal Article] Personal and Atmospheric Concentrations of Ozone in Southeastern Hyogo Prefecture, Japan (2012)
  • Author(s): N. Tang
  • Journal Title: Chemical and Pharmaceutical Bulletin Volume: 60 Issue: 8 Pages: 962-966
  • DOI: 10.1248/cpb.c12-00105
  • NAID: 130001852506
  • ISSN: 0009-2363, 1347-5223
  • Peer Reviewed
• [Journal Article] On-Line Concentration and Fluorescence Determination HPLC for Polycyclic Aromatic Hydrocarbons in Seawater Samples and Its Application to Japan Sea (2012)
  • Author(s): Li Ying
  • Journal Title: Chemical and Pharmaceutical Bulletin Volume: 60 Issue: 4 Pages: 531-535
  • DOI: 10.1248/cpb.60.531
  • NAID: 130001852445
  • ISSN: 0009-2363, 1347-5223
  • Peer Reviewed
• [Journal Article] Analysis of 8-hydroxy-2’-deoxyguanosine in human urine using hydrophilic interaction chromatography with tandem mass spectrometry (2012)
  • Author(s): C. Hosozumi
  • Journal Title: J. Chromatogr. B Volume: 893 - 894 Pages: 173-176
  • DOI: 10.1016/j.jchromb.2012.02.043
  • Peer Reviewed
• [Journal Article] Emission and transport of particulate PAHs in Northeast Asia (2012)
  • Author(s): Inomata, Y., Kajino, M., Sato, K., Ohara, T., Kurokawa, J., Ueda, H., Tang, N., Hayakawa, K., Ohizumi, T., Akimoto, H
  • Journal Title: Environ. Sci. Technol Volume: 46(9) Issue: 9 Pages: 4941-4949
  • DOI: 10.1021/es300391w
  • Peer Reviewed
• [Journal Article] Gene expression changes of phase I and II metabolizing enzymes induced by PAH derivatives (2012)
  • Author(s): Bekki, K., Takigami, H., Suzuki, G., Toriba, A., Tang, N., Kameda, T., Hayakawa, K.
  • Journal Title: Polycycl. Aromat. Comp Volume: 32(2) Issue: 2 Pages: 141-153
  • DOI: 10.1080/10406638.2011.640733
  • Peer Reviewed
• [Journal Article] Atmospheric formation of hydroxynitrofluoranthene from photo chemical reactions of 2-nitrofluoranthene (2012)
  • Author(s): T. Kameda, A. Akiyama, A. Toriba, N. Tang, K. Hayakawa
  • Journal Title: Polycyclic Aromat. Compd. Volume: (in press) Issue: 2 Pages: 177-187
  • DOI: 10.1080/10406638.2011.654307
  • Peer Reviewed
• [Journal Article] Characteristics of atmospheric polycyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarnons in Hanoi-Vietnam, as a typical motorbike city (2012)
  • Author(s): Pham, C. T., Kameda, T., Toriba A., Tang, N., Hayakawa, K
  • Journal Title: Polycycl. Aromat. Comp Volume: 32(2) Issue: 2 Pages: 296-312
  • DOI: 10.1080/10406638.2012.679015
  • Peer Reviewed
• [Journal Article] 金沢市内における大気粉塵中多環芳香族炭化水素類およびニトロ多環芳香族炭化水素類の最近12年間の変遷 (2012)
  • Author(s): 濱寛貴，徳田貴裕，伊崎陽彦，大野友子，渡辺有梨，神田哲雄，唐寧，亀田貴之，鳥羽陽，早川和一
  • Journal Title: 大気環境学会誌 Volume: 47 Pages: 1-8
  • NAID: 10030039791
  • Peer Reviewed
• [Presentation] 立山室堂の積雪中無機イオン及び多環芳香族炭化水素類の由来推定 (2014)
  • Author(s): 袴田真理子，立松路也，唐 寧，鳥羽 陽，青木一真，早川和一
  • Organizer: 第31回イオンクロマトグラフィー討論会
  • Place of Presentation: 東京
  • Year and Date: 2014-11-20 – 2014-11-21
• [Presentation] 日本海及び中国長江における多環芳香族炭化水素類の濃度推移 (2014)
  • Author(s): 牧野史弥，唐 寧，鳥羽 陽，功刀正行，早川和一
  • Organizer: 日本薬学会北陸支部第126回例会
  • Place of Presentation: 石川
  • Year and Date: 2014-11-16
• [Presentation] HPLC-蛍光検出法による実大気中benzo[c]fluorene の分析と大気変異原性への寄与推定 (2014)
  • Author(s): 森崎博志，中村志歩，唐 寧，鳥羽 陽，早川和一
  • Organizer: 日本薬学会北陸支部第126回例会
  • Place of Presentation: 石川
  • Year and Date: 2014-11-16
• [Presentation] 典型的な製鉄都市室蘭の大気粉塵と土壌の多環芳香族炭化水素とニトロ多環芳香族炭化水素 (2014)
  • Author(s): 森崎博志，唐 寧，小林茉緒，鳥羽 陽，芥川智子，酒井茂克，早川和一
  • Organizer: 日本分析化学会第63年会
  • Place of Presentation: 広島
  • Year and Date: 2014-09-17 – 2014-09-19
• [Presentation] 首都圏3地点における大気中PAH/NPAH濃度の長期変動 (2014)
  • Author(s): 鈴木元気，森川多津子，唐 寧，鳥羽 陽，早川和一
  • Organizer: 第55回大気環境学会年会
  • Place of Presentation: 愛媛
  • Year and Date: 2014-09-17 – 2014-09-19
• [Presentation] 輪島の大気中多環芳香族炭化水素類の主要発生源の追跡 (2014)
  • Author(s): 唐 寧，鳥羽 陽，亀田貴之，早川和一
  • Organizer: 第74回分析化学討論会
  • Place of Presentation: 福島
  • Year and Date: 2014-05-24 – 2014-05-25
• [Presentation] 中国の異なる砂漠地域で採集した黄砂の物性比較 (2013)
  • Author(s): 唐 寧、中坪良平、島 正之、亀田貴之、鳥羽 陽、早川和一
  • Organizer: 第54回大気環境学会年会
  • Place of Presentation: 新潟
• [Presentation] 中国上海の大気中多環報告族炭化水素類の汚染調査 (2013)
  • Author(s): 唐 寧、鳥羽 陽、亀田貴之、早川和一
  • Organizer: フォーラム2013：衛生薬学・環境トキシコロジー
  • Place of Presentation: 福岡
• [Presentation] 新規両性イオン型繊維状吸着材の室内中臭気成分吸着除去への応用 (2013)
  • Author(s): 唐 寧、PHAM Chau Thuy、井上嘉則、上茶谷若、加藤敏文、齊藤 満、早川和一
  • Organizer: 日本分析化学会第62年会
  • Place of Presentation: 大阪
• [Presentation] Evaluation of personal exposure ozone by using indirect photometric ion chromatography (2012)
  • Author(s): Tang N，Yoda Y，Huang C，Kameda T，Toriba A，Hayakawa K，Shima M
  • Organizer: 第53回大気環境学会年会
  • Place of Presentation: 横浜
• [Presentation] 東アジアの都市における大気中多環芳香族炭化水素類の汚染とその推移 (2012)
  • Author(s): 唐寧，島正之，亀田貴之，鳥羽陽，早川和一
  • Organizer: 日本分析化学会第61年会
  • Place of Presentation: 金沢
  • Invited
• [Book] Environmental Forensics-Proceedings of the 2011 INEF Conference (2012)
  • Author(s): Tang N，Hama H，Kameda T，Toriba A，Hayakawa K
  • Total Pages: 345
  • Publisher: Royal Society of Chemistry
• [Book] Handbook of Polycyclic Aromatic Hydrocarbons:Chemistry， Occurrence and Health Issues (2012)
  • Author(s): Kameda T，Akiyama A，Toriba A，Tang N，Hayakawa K
  • Total Pages: 409
  • Publisher: Nova Science Publishers