| Project/Area Number |
24590778
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Tohoku University |
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Principal Investigator |
SAITO Mariko 東北大学, 医学(系)研究科(研究院), 助教 (80404234)
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| Co-Investigator(Kenkyū-buntansha) |
KAMIGAKI Taro 東北大学, 大学院医学系研究科, 助教 (80451524)
SUZUKI Akira 東北大学, 大学院医学系研究科, 助教 (20443989)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | デングウイルス / サーベイランス / フィリピン / デング熱 / 国際研究者交流 / 国際研究者交流（フィリピン） |
|---|
| Outline of Final Research Achievements |
The outpatient and inpatient cases with fever within 5 days were enrolled at Tarlac Provincial Hospital, Philippines. Blood (whole blood and filter paper), urine, saliva were taken from the cases. Dengue virus were propagated from the serum and serotyping was determined by real-time RT-PCR.
Between May 2014 to March 2015, total of 369(outpatients) and 95(inpatients) cases were enrolled. Serum were collected from 371 cases and 87 cases were RT-PCR positive. Among the 230 cases which were tested both NS1 rapid test and RT-PCR, the sensitivity of NS1 rapid test against RT-PCR was 30% and specificity was 96%. There were no significant correlation between the symptoms (cough, headache, joint pain, vomiting, abdominal pain,rash, bleeding) and RT-PCR among the outpatients. Further analysis will be conducted.
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