| Project/Area Number |
24590780
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Tohoku University |
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Principal Investigator |
Satoh Shizuko 東北大学, 歯学研究科(研究院), 助教 (60225274)
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| Co-Investigator(Kenkyū-buntansha) |
SHOJI NORIAKI 東北大学, 大学病院, 講師 (70250800)
SASANO TAKASHI 東北大学, 大学院歯学研究科, 教授 (10125560)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 口腔乾燥症 / 小唾液腺分泌唾液 / 高齢者 / 震災ストレス / 東日本大震災 / 栄養不良 / 小唾液腺 / 口腔乾燥感 / 味覚異常感 / 食欲不振 / 体調不良 / １０品目食品摂取 / 小唾液腺分泌量測定 |
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| Outline of Final Research Achievements |
To clarify that minor salivary gland flow rate (MF) seem to be as a key feature of xerostomia in the elderly, MF in the lower labial mucosa was compared in xerostomia and control subjects using the iodine-starch filter paper method. Moreover, ｓtimulated whole salivary flow rates were also measured. As the ｒesults, Both labial-MF and stimulated-WF were significantly lower in xerostomia subjects than in controls. There was no correlation between labial-MF and stimulated-WF in xerostomia subjects. In xerostomia subjects compared to controls, there was a significantly larger reduction in labial-MF than in stimulated-WF. Though after 3 years the great east japn earth earthquake,in the elderly patients with xerostomia, psychological stress lasted and MF has still redused, whereas stimulates-WF has recovered to normal level. Moreover, in elderly patients with xerostomia, inadequate nutrition, appetite loss and poor health were significantly seen than in control without xerostomia.
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