The study for biological future of the interval cancers detected in mammography screening.
| Project/Area Number |
24590781
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Tohoku University |
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Principal Investigator |
Suzuki Akihiko 東北大学, 医学(系)研究科(研究院), 准教授 (60375045)
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| Co-Investigator(Kenkyū-buntansha) |
Ishida TAKANORI 東北大学, 医学系研究科, 准教授 (00292318)
Umeda MIKA 東北大学, 医学系研究科, 准教授 (20292344)
Ohuchi NORIAKI 東北大学, 医学系研究科, 教授 (90203710)
河合 賢朗 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), その他部局等, 研究員 (80513530)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 乳がん検診 / マンモグラフィ / 中間期がん / 超音波 / 超音波検査 / 総合判定 / マンモグラフィー / 精度管理 / 癌がん登録 / J-START |
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| Outline of Final Research Achievements |
Although mammography is the only method that has evidence supporting mortality reduction for breast cancer, accuracy is reduced in women with high-density breast tissue and in young women. We have continued the study for interval caner for a decade. The article about the primary endpoint of “the Japan Strategic Anti-cancer Randomized Trial (J-START)”was published in the Lancet in January 2016. Interval cancers were reported as 35 in the control group and 18 in the intervention group. Interval cancers, which were detected in the intervention group, were significantly lower then control group. We are continuing analyze the biological future of the interval cancers.
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Report
(5 results)
Research Products
(15 results)
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[Journal Article] Sensitivity and specificity of mammography and adjunctive ultrasonography to screen for breast cancer in the Japan Strategic Anti-cancer Randomized Trial (J-START): a randomised controlled trial.2016
Author(s)
Ohuchi N., Suzuki A., Sobue T., Kawai M., Yamamoto S., Zheng Y. F., Shiono Y. N., Saito H., Kuriyama S., Tohno E., Endo T., Fukao A., Tsuji I., Yamaguchi T., Ohashi Y., Fukuda M., Ishida T
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Journal Title
The Lancet
Volume: 387
Issue: 10016
Pages: 341-348
DOI
Related Report
Peer Reviewed / Open Access
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