Molecular epidemiology for depression in cancer
| Project/Area Number |
24590831
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | National Cancer Center Japan |
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Principal Investigator |
Ogawa Asao 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長 (10466196)
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| Co-Investigator(Kenkyū-buntansha) |
UCHITOMI Yosuke 国立がん研究センター, 支持療法開発センター, センター長 (60243565)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 疫学 / 分子疫学 / 臨床精神分子遺伝学 / 緩和医療 / 精神腫瘍分子遺伝学 |
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| Outline of Final Research Achievements |
Various risk factors for depression in cancer patients have been suggested but have been examined separately in studies with relatively small sample sizes. The present study examined the biopsychosocial risk factors of depression in cancer, focusing on molecular epidemiological factors. We recruited newly diagnosed as having cancer before first line treatment consecutively. We aim to identify comprehensive geriatric assessment (CGA) based clinical factors associated with depression. Logistic regression models were fitted to estimate the odds ratio (OR) to assess the association of various variables with mild to severe depression. And, we exploratory conduct GWAS of depressive symptoms.
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Report
(5 results)
Research Products
(108 results)
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[Journal Article] Validation of the Japanese Version of Edmonton Symptom Assessment System-Revised.2015
Author(s)
Yokomichi N, Morita T, Nitto A, Takahashi N, Miyamoto S, Nishie H, Matsuoka J, Sakurai H, Ishihara T, Mori M, Trumi Y, Ogawa A
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Journal Title
Journal of Pain and Symptom Management
Volume: 50
Issue: 5
Pages: 718-23
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] The Association Between Depressive Symptoms and Age in Cancer Patients: A Multicenter Cross-Sectional Study.J Pain Symptom Manage.2015
Author(s)
Wada S, Shimizu K, Inoguchi H, Shimoda H, Yoshiuchi K, Akechi T, Uchida M, Ogawa A, Fujisawa D, Inoue S, Uchitomi Y, Matsushima E
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Journal Title
10.1016/j.jpainsymman.2015.07.011
Volume: 50
Issue: 6
Pages: 768-77
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Impact of depression on health utility value in cancer patients.2015
Author(s)
Fujisawa D, Inoguchi H, Shimoda H, Yoshiuchi K, Inoue S, Ogawa A, Okuyama T, Akechi T, Mimura M, Shimizu K, Uchitomi Y.
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Journal Title
Psycho-oncology
Volume: 25(5)
Issue: 5
Pages: 491-495
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Personality traits and coping styles explain anxiety in lung cancer patients to a greater extent than other factors.2015
Author(s)
Shimizu K, Nakaya N, Saito-Nakaya K, Akechi T, Ogawa A, Fujisawa D, Sone T, Yoshiuchi K, Goto K, Iwasaki M, Tsugane S, Uchitomi Y.
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Journal Title
Jpn J Clin Oncol
Volume: 45
Issue: 5
Pages: 456-63
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Establishing Cut-off Points for Defining Symptom Severity Using the Edmonton Symptom Assessment System-Revised Japanese Version2015
Author(s)
Yamaguchi T, Morita T, Nitto A, Takahashi N, Miyamoto S, Nishie H, Matsuoka J, Sakurai H, Ishihara T, Tarumi Y, Ogawa Asao
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Journal Title
Journal of Pain and Symptom Management
Volume: 51
Issue: 2
Pages: 292-7
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Association between adjuvant regional radiotherapy and cognitive function in breast cancer patients treated with conservation therapy.2014
Author(s)
Shibayama O, Yoshiuchi K, Inagaki M, Matsuoka Y, Yoshikawa E, Sugawara Y, Akechi T, Wada N, Imoto S, Murakami K, Ogawa A, Akabayashi A, Uchitomi Y.
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Journal Title
Cancer Med
Volume: 3
Issue: 3
Pages: 702-709
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] mpaired mental health among the bereaved spouses of cancer patients2013
Author(s)
Mariko Asai, Nobuya Akizuki, Maiko Fujimori, Ken Shimizu, Asao Ogawa, Yutaka Matsui, Tatsuo Akechi, Kuniaki Itoh, Masafumi Ikeda, Ryuichi Hayashi, Taira Kinoshita, Atsushi Ohtsu, Kanji Nagai,Hiroya Kinoshita, and Yosuke Uchitomi
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Journal Title
Psycho-Oncology
Volume: 22
Issue: 5
Pages: 995-1001
DOI
Related Report
Peer Reviewed
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[Journal Article] Clinical biopsychosocial risk factors for depression in lung cancer patients: a comprehensive analysis using data from the Lung Cancer Database Project2012
Author(s)
Shimizu K, Nakaya, N.,Saito-Nakaya, K.,Akechi, T.,Yamada, Y.,Fujimori, M.,Ogawa, A.,Fujisawa, D.,Goto, K.,Iwasaki, M.,Tsugane, S.,Uchitomi, Y
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Journal Title
Ann Oncol
Volume: 23
Issue: 8
Pages: 1973-1979
DOI
Related Report
Peer Reviewed
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[Journal Article] Patients perception of the usefulness of a question prompt sheet for advanced cancer patients when deciding the initial treatment : a randomized, controlled trial2011
Author(s)
Shirai, Y., Fujimori, M., Ogawa, A., Yamada, Y., Nishiwaki, Y., Ohtsu, A., Uchitomi, Y.
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Journal Title
Psychooncology
Volume: (Epub ahead of print)
Issue: 7
Pages: 706-713
DOI
Related Report
Peer Reviewed
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[Journal Article] Availability of Psychiatric Consultation-Liaison Services as an Integral Component of Palliative Care Programs at Japanese Cancer Hospitals2011
Author(s)
Ogawa, A., Nouno, J., Shirai, Y., Shibayama, O., Kondo, K., Yokoo, M., Takei, H., Koga, H., Fujisawa, D., Shimizu, K., and Uchitomi, Y.
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Journal Title
Jpn J Clin Oncol
Volume: 42
Issue: 1
Pages: 42-52
DOI
Related Report
Peer Reviewed
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[Presentation] 高齢者機能評価2015
Author(s)
小川朝生
Organizer
第２８回日本内視鏡外科学会総
Place of Presentation
大阪市
Year and Date
2015-12-10
Related Report
Invited
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[Presentation] 不眠へのアプローチ2015
Author(s)
小川朝生
Organizer
第28回日本サイコオンコロジー学会総会
Place of Presentation
広島県広島市
Year and Date
2015-09-18
Related Report
Invited
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[Presentation] 認知症の緩和ケア2015
Author(s)
小川朝生
Organizer
第65回日本病院学会
Place of Presentation
長野県北佐久郡軽井沢町
Year and Date
2015-06-18
Related Report
Invited
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