New strategy for blood pressure management with detection of inappropriate blood pressure variability in the elderly: Development of useful cuff-less 'Wearable blood pressure sensor'
Project/Area Number |
24590878
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
General internal medicine (including Psychosomatic medicine)
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Research Institution | The University of Tokyo |
Principal Investigator |
IIJIMA KATSUYA 東京大学, 高齢社会総合研究機構, 准教授 (00334384)
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Co-Investigator(Kenkyū-buntansha) |
大田 秀隆 東京大学, 医学部附属病院, 助教 (20431869)
柴崎 孝二 東京大学, 高齢社会総合研究機構, 特任研究員 (20625735)
江頭 正人 東京大学, 医学部附属病院, 准教授 (80282630)
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Project Period (FY) |
2012-04-01 – 2015-03-31
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Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Keywords | 血圧変動 / 動脈壁硬化 / ウェアラブル血圧センシング / 動脈石灰化 / ex vivo新実験モデル構築 / 被災地 / 血圧遠隔管理システム / 高齢者 / 循環動態管理 / 血管石灰化 / 遠隔管理 / 新規実験モデル / ウェアラブル血圧センサー / 降圧管理の質 / デバイス開発 / 遠隔管理を通した健康維持 / 新規モデル実験構築 |
Outline of Final Research Achievements |
<Research No.1> After East Japan earthquake, the remote control system of blood pressure (BP) in elderly evacuees in Kamaishi city was conducted. This challenging system could reflect inadequate BP variability (BPV) quickly and accurately and may give them additional effects on awareness to health promotion and homebound prevention. <Research No.2> We developed wearable continuous BP monitoring sensor without a cuff-stress in the elderly. This device might approach to the potential to achieve the quality-up of treatment strategy with consideration for very short-term BPV. < Research No.3> We established the great experimental model of vascular calcification (VC) using organ culture of aorta. Aortas were dissected from mice and cultured with inorganic phosphate to induce VC. This organ culture ex-vivo model of VC can achieve to assess morphometric and phenotypic changes and so on. It suggests that this model will be useful to explore the molecular mechanisms of VC and senescent pathology.
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Report
(4 results)
Research Products
(66 results)
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[Journal Article] Development of a simple screening test for sarcopenia in older adults2014
Author(s)
Ishii S, Tanaka T, Shibasaki K, Ouchi Y, Kikutani T, Higashiguchi T, Obuchi SP, Ishikawa-Takata K, Hirano H, Kawai H, Tsuji T, Iijima K
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Journal Title
Geriatr Gerontol Int.
Volume: 14
Pages: 93-101
Related Report
Peer Reviewed
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[Journal Article] セカンドライフ就労を介したシニア世代の身体活動量の変化に対する検討:Aging in Placeを目指して2013
Author(s)
柴崎孝二, 飯島勝矢, 菅原育子, 矢冨直美, 前田展弘, 秋山弘子, 後藤純, 廣瀬雄一, 笈田幹弘, 佐藤祥彦, 辻哲夫, 鎌田実
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Journal Title
日本未病システム学会雑誌
Volume: 19
Pages: 107-11
Related Report
Peer Reviewed
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[Journal Article] Marked improvement of elderly postprandial hypotension by dipeptidyl peptidase IV inhibitor2013
Author(s)
Yonenaga A, Ota H, Honda M, Koshiyama D, Yagi T, Hanaoka Y, Yamamoto H, Yamaguchi Y, Iijima K, Akishita M, Ouchi Y
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Journal Title
Geriatr Gerontol Int.
Volume: 13
Pages: 227-229
Related Report
Peer Reviewed
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[Journal Article] Thrombomodulin, a novel molecule regulating inorganic phosphate-induced vascular smooth muscle cell calcification2013
Author(s)
Son BK, Akishita M, Iijima K, Ogawa S, Arai T, Ishii H, Maemura K, Aburatani H, Eto M, Ouchi Y
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Journal Title
J Mol Cell Cardiol
Volume: 56
Pages: 72-80
Related Report
Peer Reviewed
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[Journal Article] Lower Physical Activity, but not Excessive Calorie Intake, is Associated with Metabolic Syndrome in Elderly with Type 2 Diabetes Mellitus: Japanese Elderly Diabetes Intervention Trial (J-EDIT)2012
Author(s)
Iijima K, Iimuro S, Ohashi Y, Sakurai T, Umegaki H, Araki A, Yoshimura Y, Ouchi Y, Ito H, J-EDIT Investigator Group
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Journal Title
Geriatr Gerontol Int
Volume: Suppl. 1
Pages: 68-76
Related Report
Peer Reviewed
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[Journal Article] 在宅医療推進における円滑な情報共有システムを導入した新たな多職種連携の試み: 千葉県柏市における2012
Author(s)
飯島勝矢, 吉江悟, 木全真理, 井堀幹夫, 山本拓真, 後藤純, 柴崎孝二, 藤田伸輔, 高林克日己, 鎌田実, 辻哲夫
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Journal Title
在宅医療の推進. 癌と化学療法, 39(Suppl.I), 51-54, 2012
Volume: 39(Suppl 1)
Pages: 51-54
Related Report
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[Presentation] NEW ATTEMPT OF IDEAL SECOND LIFE WITH A SENSE OF FULFILLMENT IN COMMUNITYDWELLING SENIORS: TO ACHIEVE ‘AGING IN PLACE’2013
Author(s)
Kouji SHIBASAKI, Katsuya IIJIMA, Ikuko SUGAWARA, Hiroto MUROHASHI, Naomi YATOMI, Nobuhiro MAEDA, Tetsuo TSUJI, Minoru KAMATA, Hiroko AKIYAMA, Jun GOTO, Yuichi HIROSE, Mikihiro OIDA and Yoshihiko SATO
Organizer
International Association of Gerontology and Geriatrics (IAGG) 2013
Place of Presentation
ソウル、韓国
Related Report
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[Presentation] 自己評価による多職種連携において共有すべき情報の検証~千葉県柏市における在宅医療推進の新たな取り組み~2013
Author(s)
木全真理, 飯島勝矢, 吉江悟, 後藤純, 井堀幹夫, 山本拓真, 久保眞人, 平江良成, 藤田伸輔 , 高林克日己, 鎌田実, 辻哲夫
Organizer
第15回 日本在宅医学会学術集会
Place of Presentation
ひめぎんホール(愛媛県)
Related Report
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[Presentation] 主治医-副主治医制による在宅診療のバックアップシステムの構築~千葉県柏市における在宅医療推進の新たな取り組み~2013
Author(s)
久保眞人, 飯島勝矢, 木全真理, 吉江悟, 後藤純, 井堀幹夫, 山本拓真, 平江良成, 藤田伸輔 , 高林克日己, 鎌田実, 辻哲夫
Organizer
第15回 日本在宅医学会学術集会
Place of Presentation
ひめぎんホール(愛媛県)
Related Report
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[Presentation] 身体の活動量の意義
Author(s)
飯島勝矢
Organizer
2012年 日本老年医学会・学術集会
Place of Presentation
東京国際フォーラム(東京都)
Related Report
Invited
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