Analysis of the mechanism and appropriate therapy of persistent atrial fibrillation
Project/Area Number |
24591061
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Circulatory organs internal medicine
|
Research Institution | Kumamoto University |
Principal Investigator |
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
|
Keywords | 持続性心房細動 / マッピング / カテーテルアブレーション / 心房細動 |
Outline of Final Research Achievements |
Persistent atrial fibrillation was maintained by the disorganized activation, which was mainly observed over the complex fractionated electrogram (CFAE) region. The CFAE area was caused by the heterogeneous conduction property of the left atrial myocardium and was closely associated with the cardiac pericardial fat tissue. Linear left atrial roof lesion and subsequent CFAE ablation after the pulmonary vein isolation performed in a stepwise fashion was effective for the termination of persistent atrial fibrillation.
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Report
(4 results)
Research Products
(13 results)