• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The effect of cardiac rehabilitation on the myokines in patients with heart failura

Research Project

Project/Area Number 24591066
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Circulatory organs internal medicine
Research InstitutionOsaka City University

Principal Investigator

YOSHIYAMA Minoru  大阪市立大学, 医学(系)研究科(研究院), 教授 (30240956)

Co-Investigator(Renkei-kenkyūsha) IZUMI Yasukatsu  大阪市立大学大学, 医学研究科, 准教授 (10347495)
NAKAMURA Yasuhiro  大阪市立大学, 医学研究科, 登録医 (50457991)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords心臓リハビリテーション / マイオカイン / 心血管保護効果 / 運動耐容能 / 慢性心不全 / 薬物療法 / 心臓リハビリ / 非薬物療法
Outline of Final Research Achievements

Exercise tolerance, not left ventricular ejection fraction, was important prognostic indicator for patients with chronic heart failure. Cardiac rehabilitation can prevent major cardiac adverse events. However, this mechanism is still unknown. Skeletal muscle has recently been identified as an organ that produces and releases cytokines, named “myokines.” We investigated whether serum brain derived neurotropic factor (BDNF) level or irisin, which is one of myokines, level at discharge could predict the prognosis in patients with heart failure (HF). This study consisted of patients who were hospitalized for worsening heart failure and had cardiac rehabilitation at least 1 week. We measured serum BNDF, and irisin. One-year follow-up was completed in all of the patients. Kaplan-Meier analysis demonstrated that the event free rate was decreased in the low BDNF or irisin group. Myokines level at discharge may be a useful biomarker for the prognosis in patients with HF.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (87 results)

All 2015 2014 2013 2012

All Journal Article (32 results) (of which Peer Reviewed: 22 results,  Open Access: 2 results) Presentation (55 results)

  • [Journal Article] Percutaneous Carbon Dioxide Treatment using a Gas Mist Generator Enhances the Collateral Blood Flow in the Ischemic Hindlimb2015

    • Author(s)
      Izumi, Y
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 22 Issue: 1 Pages: 38-51

    • DOI

      10.5551/jat.23770

    • NAID

      130004677973

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Characteristic patterns of the longitudinal and circumferential distribution of calcium deposits by parent coronary arteries observed from computed tomography angiography.2015

    • Author(s)
      1.Ehara S, Matsumoto K, Hasegawa T, Otsuka K, Sakaguchi M, Shimada K, Yoshikawa J, Yoshiyama M.
    • Journal Title

      Heart and Vessels

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Repeated remote ischemic conditioning attenuates left ventricular remodeling via exosome-mediated intercellular communication on chronic heart failure after myocardial infarction.2015

    • Author(s)
      Yamaguchi T, Izumi Y, Nakamura Y, Yamazaki T, Shiota M, Sano S, Tanaka M, Osada-Oka M, Shimada K, Miura K, Yoshiyama M, Iwao H.
    • Journal Title

      Int J Cardiol

      Volume: 178 Pages: 239-246

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Association between chronic kidney disease and thoracic aortic atherosclerosis detected using transesophageal echocardiography.2014

    • Author(s)
      Matsumura Y, Sugioka K, Fujita S, Ito A, Iwata S, Yoshiyama M.
    • Journal Title

      Atherosclerosis

      Volume: 1 Pages: 301-306

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Hydrogen gas attenuates embryonic gene expression and prevents left ventricular remodeling induced by intermittent hypoxia in cardiomyopathic hamsters.2014

    • Author(s)
      Kato R, Nomura A, Sakamoto A, Yasuda Y, Amatani K, Nagai S, Sen Y, Ijiri Y, Okada Y, Yamaguchi T, Izumi Y, Yoshiyama M, Tanaka K, Hayashi T.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 307 Pages: 1626-1633

    • Related Report
      2014 Annual Research Report
  • [Journal Article] A noninvasive metabolic syndrome model using an extremely small minipig, the microminipig.2014

    • Author(s)
      Yamaguchi T, Yamazaki T, Kawaguchi H, Tawa M, Nakamura Y, Shiota M, Osada-Oka M, Tanimoto A, Okamura T, Miura K, Iwao H, Yoshiyama M, Izumi Y.
    • Journal Title

      J Pharmacol Sci

      Volume: 126 Pages: 168-171

    • NAID

      130004690915

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Relationship between CHADS2 score and complex aortic plaques by transesophageal echocardiography in patients with nonvalvular atrial fibrillation.2014

    • Author(s)
      Sugioka K, Fujita S, Iwata S, Ito A, Matsumura Y, Hanatani A, Doi A, Takagi M, Naruko T, Ueda M, Yoshiyama M.
    • Journal Title

      Ultrasound Med Biol

      Volume: 40 Pages: 2358-2364

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Serial assessment of arterial stiffness by cardio-ankle vascular index for prediction of future cardiovascular events in patients with coronary artery disease2014

    • Author(s)
      Otsuka, K
    • Journal Title

      Hypertens Res

      Volume: 37 Issue: 11 Pages: 1014-1020

    • DOI

      10.1038/hr.2014.116

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chronic active Epstein-Barr virus infection complicated with multiple artery aneurysms2014

    • Author(s)
      Nishimura S, Ehara S, Hanatani A, Yoshiyama M
    • Journal Title

      Eur Heart J Cardiovsc Imaging

      Volume: 15 Issue: 11 Pages: 1255-1255

    • DOI

      10.1093/ehjci/jeu119

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced expression of hemoglobin scavenger receptor and heme oxygenase-1 is associated with aortic valve stenosis in patients undergoing hemodialysis.2014

    • Author(s)
      Inaba M, Sugioka K, Naruko T, Yunoki K, Kato Y, Shibata T, Inoue T, Ohsawa M, Yoshiyama M, Ueda M.
    • Journal Title

      Hemodial Int

      Volume: 18 Issue: 3 Pages: 632-640

    • DOI

      10.1111/hdi.12147

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Giant mycotic coronary aneurysm associated with late stent infection.2014

    • Author(s)
      Nonin S, Hasegawa T, Hirai H, Suehiro S, Yoshiyama M.
    • Journal Title

      Eur Heart J Cardiovasc Imaging.

      Volume: 15 Issue: 6 Pages: 630-630

    • DOI

      10.1093/ehjci/jet262

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Prognosis of vulnerable plaque on computed tomographic coronary angiography with normal myocardial perfusion image.2014

    • Author(s)
      Otsuka K, Fukuda S, Tanaka A, Nakanishi K, Taguchi H, Yoshiyama M, Shimada K, Yoshikawa J.
    • Journal Title

      Eur Heart J Cardiovasc Imaging.

      Volume: 15 Issue: 3 Pages: 332-340

    • DOI

      10.1093/ehjci/jet232

    • Related Report
      2014 Annual Research Report
  • [Journal Article] The strain pattern, and not Sokolow-Lyon electrocardiographic voltage criteria, is independently associated with anatomic left ventricular hypertrophy2014

    • Author(s)
      Ehara S, Hasegawa T, Matsumoto K, OtsukaY, Yamazaki T, Iguchi T, Izumi Y, Shimada K, Yoshiyama M
    • Journal Title

      Heart Vessels

      Volume: 29 Issue: 5 Pages: 638-644

    • DOI

      10.1007/s00380-013-0408-0

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Serum n-3 to n-6 polyunsaturated fatty acids ratio correlates with coronary plaque vulnerability: an optical coherence tomography study2014

    • Author(s)
      Hasegawa T, Otsuka K, Iguchi T, Matsumoto K, Ehara S, Nakata S, Nishimura S, Kataoka T, Shimada K, Yoshiyama M
    • Journal Title

      Heart Vessels

      Volume: 29 Issue: 5 Pages: 596-602

    • DOI

      10.1007/s00380-013-0404-4

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1cells2014

    • Author(s)
      Sano S, Izumi Y, Yamaguchi T, Yamazaki T, Tanaka M, Shiota M, Osada-Oka M, Nakamura Y, Wei M, Wanibuchi H, Iwao H, Yoshiyama M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 445 Issue: 2 Pages: 327-33

    • DOI

      10.1016/j.bbrc.2014.01.183

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Insulin resistance is associated with coronary plaque vulnerability: insight from optical coherence tomography analysis2014

    • Author(s)
      Iguchi T, Hasegawa T, Otsuka K, Matsumoto K, Yamazaki T, Nishimura S, Nakata S, Ehara S, Kataoka T, Shimada K, Yoshiyama M
    • Journal Title

      Eur Heart J Cardiovasc Imaging

      Volume: 15 Issue: 3 Pages: 284-291

    • DOI

      10.1093/ehjci/jet158

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Tolvaptan attenuates left ventricular fibrosis after acute myocardial infarction in rats.2013

    • Author(s)
      Yamazaki T, Nakamura Y, Shiota M, Osada-Oka M, Fujiki H, Hanatani A, Shimada K, Miura K, Yoshiyama M, Iwao H, Izumi Y.
    • Journal Title

      J Pharmacol Sci

      Volume: 123 Pages: 58-66

    • Related Report
      2013 Research-status Report
  • [Journal Article] Napkin-ring sign on coronary CT angiography for the prediction of acute coronary syndrome.2013

    • Author(s)
      Otsuka K, Fukuda S, Tanaka A, Nakanishi K, Taguchi H, Yoshikawa J, Shimada K, Yoshiyama M.
    • Journal Title

      JACC Cardiovasc Imaging

      Volume: 6 Issue: 4 Pages: 448-457

    • DOI

      10.1016/j.jcmg.2012.09.016

    • Related Report
      2013 Research-status Report
  • [Journal Article] Impact of lesion length on functional significance in intermediate coronary lesions2013

    • Author(s)
      Iguchi T, Hasegawa T, Nishimura S, Nakata S, Kataoka T, Ehara S, Hanatani A, Shimada, K, Yoshiyama M
    • Journal Title

      Clin Cardiol

      Volume: 36 Issue: 3 Pages: 172-177

    • DOI

      10.1002/clc.22076

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Tolvaptan improves left ventricular dysfunction after myocardial infarction in rats.2012

    • Author(s)
      Yamazaki T, Izumi y Nakamura Y, Yamashita N, Fujiki H, Osada-Oka M, Shiota M, Hanatani A, Shimada K, Iwao H, Yoshiyama M.
    • Journal Title

      Circ Heart Fail.

      Volume: 5 Issue: 6 Pages: 794-802

    • DOI

      10.1161/circheartfailure.112.968750

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Peri-atrial epicardial adipose tissue is associated with new-onset nonvalvular atrial fibrillation.2012

    • Author(s)
      Nakanishi K, Fukuda S, Tanaka A, Otsuka K, Sakamoto M, Taguchi H, Yoshikawa J, Shimada K, Yoshiyama M.
    • Journal Title

      Circ J.

      Volume: 76 Pages: 2748-54

    • NAID

      10031126044

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Preliminary observations of passive exercise using whole body periodic acceleration on coronary microcirculation and glucose tolerance in patients with type 2 diabetes.2012

    • Author(s)
      Sakaguchi M, Fukuda S, Shimada K, Izumi Y, Izumiya Y, Nakamura Y, Nakanishi K, Otsuka K, Ogawa H, Fujita M, Yoshikawa J, Yoshiyama M.
    • Journal Title

      J Cardiol.

      Volume: 60 Issue: 4 Pages: 283-7

    • DOI

      10.1016/j.jjcc.2012.05.006

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Therapeutic administration of IL-11 exhibits the postconditioning effects against ischemia-reperfusion injury via STAT3 in the heart2012

    • Author(s)
      Obana M, Miyamoto K, Murasawa S, Iwakura T, Hayama A, Yamashita T,Shiragaki M, Kumagai S, Miyawaki A, Takewaki K, Matsumiya G, Maeda M, Yoshiyama M, Nakayama H, Fujio Y.
    • Journal Title

      Am J Physiol Heart Circ. Physiol

      Volume: 303(5) Issue: 5 Pages: 569-77

    • DOI

      10.1152/ajpheart.00060.2012

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Impaired coronary flow reserve as a marker of microvascular dysfunction to predict long-term cardiovascular outcomes, acute coronary syndrome and the development of heart failure.2012

    • Author(s)
      Nakanishi K, Fukuda S, Shimada K, Miyazaki C, Otsuka K, Maeda K, Miyahana R, Kawarabayashi T, Watanabe H, Yoshikawa J, Yoshiyama M.
    • Journal Title

      Circ J.

      Volume: 76 Pages: 1958-64

    • NAID

      10030504808

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Prognostic value of aortic valve area index in asymptomatic patients with severe aortic stenosis2012

    • Author(s)
      Toshio Saito, Takashi Muro, Hisateru Takeda, Eiichi Hyodo, Shoichi Ehara, Yasuhiro Nakamura, Akihisa Hanatani, Kenei Shimada, Minoru Yoshiyama
    • Journal Title

      Am J Cardiol

      Volume: 110 Issue: 1 Pages: 93-97

    • DOI

      10.1016/j.amjcard.2012.02.056

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Comparison of two-dimensional and real-time three-dimensional transesophageal echocardiography in the assessment of aortic valve area.2012

    • Author(s)
      Furukawa A, Abe Y, Tanaka C, Ito K, Tabuchi I, Osawa K, Kino N, Nakagawa E, Komatsu R, Haze K, Yoshiyama M, Yoshikawa J, Naruko T, Itoh A.
    • Journal Title

      J Cardiol.

      Volume: 59 Issue: 3 Pages: 337-43

    • DOI

      10.1016/j.jjcc.2012.01.011

    • NAID

      10031187754

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Novel device that produces carbon dioxide mist for myocardial infarction treatment in rats.2012

    • Author(s)
      Yamazaki T, Izumi Y, Nakamura Y, Hanatani A, Shimada K, Muro T, Shiota M, Iwao H, Yoshiyama M.
    • Journal Title

      Circ J.

      Volume: 76 Pages: 1203-12

    • NAID

      10030132718

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hyperintense plaque identified by magnetic resonance imaging relates to intracoronary thrombus as detected by optical coherence tomography in patients with angina pectoris2012

    • Author(s)
      Shoichi Ehara, Takao Hasegawa, Shinji Nakata, Kenji Matsumoto, Satoshi Nishimura, Tomokazu Iguchi, Toru Kataoka, Junichi Yoshikawa, Minoru Yoshiyama
    • Journal Title

      Eur Heart J Cardiovasc Imaging

      Volume: 13 Issue: 5 Pages: 394-399

    • DOI

      10.1093/ehjci/jer305

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Non-obstructive low attenuation coronary plaque predicts three-year acute coronary syndrome events in patients with hypertension: multidetector computed tomographic study.2012

    • Author(s)
      Nakanishi K, Fukuda S, Shimada K, Ehara S, Inanami H, Matsumoto K, Taguchi H, Muro T, Yoshikawa J, Yoshiyama M.
    • Journal Title

      J Cardiol.

      Volume: 59 Issue: 2 Pages: 167-75

    • DOI

      10.1016/j.jjcc.2011.11.010

    • NAID

      10030582245

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Erythrocyte-rich thrombus aspirated from patients with ST-elevaiton myocardial infarction : associationi with oxidative stress and its impact on myocardial reperfusion2012

    • Author(s)
      Yunoki K, Ueda M, et al
    • Journal Title

      Eur Heart J

      Volume: (in press) Issue: 12 Pages: 1480-90

    • DOI

      10.1093/eurheartj/ehr486

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] The antifibrotic agent pirfenidone inhibits angiotensin II-induced cardiac hypertrophy in mice.2012

    • Author(s)
      Yamazaki T, Yamashita N, Izumi Y, Nakamura Y, Shiota M, Hanatani A, Shimada K, Muro T, Iwao H, Yoshiyama M.
    • Journal Title

      Hypertens Res.

      Volume: 35 Issue: 1 Pages: 34-40

    • DOI

      10.1038/hr.2011.139

    • NAID

      10030642721

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Circadian variation in coronary flow velocity reserve and its relation to ホア1-sympathetic activity in humans.2012

    • Author(s)
      Fukuda S, Shimada K, Maeda K, Kawasaki T, Kono Y, Miyahana R, Jissho S, Taguchi H, Yoshiyama M, Fujita M, Yoshikawa J.
    • Journal Title

      Int J Cardiol.

      Volume: 157 Issue: 2 Pages: 216-20

    • DOI

      10.1016/j.ijcard.2010.12.052

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 超小型ミニブタを用いたメタボリック症候群モデル作製2014

    • Author(s)
      泉 康雄, 山崎 貴紀, 中村 泰浩, 島田 健永, 葭山 稔, 岩尾 洋
    • Organizer
      日本高血圧学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-10-17 – 2014-10-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Visit-to-Visit平均透析中血圧高値は透析患者の大動脈弁狭窄症進行促進因子である2014

    • Author(s)
      則岡直樹, 岩田 真一, 柳 志郎, 八木 秀也, 吉田 啓子, 蒔田 直記, 白井 たから, 石井 英, 紙森 公雄, 太田 剛弘, 葭山 稔
    • Organizer
      日本高血圧学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-10-17 – 2014-10-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 若年健康女性医療従事者における夜勤が夜間血圧に与える影響2014

    • Author(s)
      北田 諒子, 岩田 真一, 花谷 彰久, 杉岡 憲一, 葭山 稔
    • Organizer
      日本高血圧学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-10-17 – 2014-10-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Long-term follow up results of balloon angioplasty for focal renal artery stenosis in young female patients with renovascular hypertension.2014

    • Author(s)
      Kazuki Mizutani , Akira Itoh , Kei Yunoki , Ryushi Komatsu , Takahiko Naruko , MinoruYoshiyama.
    • Organizer
      ESC Congress
    • Place of Presentation
      Barcelona (Spain)
    • Year and Date
      2014-08-30 – 2014-09-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Vascular functional and morphological alterations in smokers with varenicline therap.2014

    • Author(s)
      Kobayashi M, Takemoto Y, Norioka N, Suto T, Yoshiyama M.
    • Organizer
      ESC Congress
    • Place of Presentation
      Barcelona(Spain)
    • Year and Date
      2014-08-30 – 2014-09-03
    • Related Report
      2014 Annual Research Report
  • [Presentation] Long-term results of endovascular therapy for below-the-knee lesions in patients with critical limb ischemia in our institution2014

    • Author(s)
      Matsuo Masanori, Nishioka Hiroki, Katayama Hisashi, Kakihara Jun, Koga Yuki, Fujimoto Kouhei, Kasayuki Noriaki, Shimada Kenei, Yoshiyama Minoru.
    • Organizer
      日本心血管インターベンション治療学会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2014-07-24 – 2014-07-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Histlogical findings of Fibromuscular dysplasia in Optical Coherance Tomography2014

    • Author(s)
      Mizutani Kazuki, Itoh Akira, Yunoki Kei, Komatsu Ryushi, Haze Kazuo, Naruko Takahiko, Yoshiyama Minoru.
    • Organizer
      日本心血管インターベンション治療学会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2014-07-24 – 2014-07-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Risk Stratification in Brugada Syndrome by Using the Combination of T-wave-alternans and Heart Rate Variability2014

    • Author(s)
      Sakamoto Shogo, Takagi Masahiko, Tatsumi Hiroaki, Doi Atsushi, Yoshiyama Minoru.
    • Organizer
      日本心電図学会
    • Place of Presentation
      ザ・プリンスパークタワー東京(東京都・港区)
    • Year and Date
      2014-07-22 – 2014-07-25
    • Related Report
      2014 Annual Research Report
  • [Presentation] 虚血性心疾患患者の血中バイオマーカーにおける酸化・抗酸化バランス 血漿中ミエロペルオキシダーゼ(MPO)値と血清パラオキソナーゼ-1(PON-1)値の関連2014

    • Author(s)
      柚木 佳, 成子 隆彦, 吉山 智貴, 杉岡 憲一, 仲川 将志, 小松 龍士, 稲葉 真由美, 土師 一夫, 葭山 稔, 上田 真喜子
    • Organizer
      日本動脈硬化学会総会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] 内皮機能検査「FMD」の最新の知見 baIMTとFMD どう使う? 血管機能評価と血管形態評価2014

    • Author(s)
      竹本 恭彦, 井口 朋和, 則岡 直樹, 首藤 太一, 葭山 稔
    • Organizer
      日本動脈硬化学会総会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] athological and Immunohistochcmical Findings at Sites of Restenosis and Late Stent Thrombosis after Drug-Eluting Stents2014

    • Author(s)
      Nakagawa Masashi, Naruko Takahiko, Sugioka Kenichi, Inaba Mayumi, Miyazawa Tsuyoshi, Kamihata Hiroshi, Takanashi Shyuichirou, Yoshiyama Minoru, Ueda Makiko.
    • Organizer
      日本動脈硬化学会総会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Aortic Arch Calcification on chest X-ray is a simple predictor of Aortic Arch Complex Plaques in patients with Nonvalvular Atrial Fibrillation2014

    • Author(s)
      Ito Asahiro, Sugioka Kenichi, Fujita Suwako, Iwata Shinichi, Matsumura Yoshiki, Naruko Takahiko, Ueda Makiko, Yoshiyama Minoru.
    • Organizer
      日本動脈硬化学会総会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Relationship between CHADS2 score and complex aortic plaques by transesophageal echocardiography in patients with nonvalvular atrial fibrillation2014

    • Author(s)
      Fujita Suwako, Sugioka Kenichi, Iwata Shinichi, Matsumura Yoshiki, Nakagawa Masashi, Doi Atsushi, Takagi Masahiko, Ueda Makiko, Yoshiyama Minoru.
    • Organizer
      日本動脈硬化学会総会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] Serum Levels of High-density Lipoprotein-Associated Paraoxonase-1 Predict Recurrent Cardiovascular Events after Drug-Eluting Stent Implantation in Patients with Stable Angina Pectoris2014

    • Author(s)
      Yoshiyama Tomotaka, Yunoki Kei, Komatsu Ryushi, Haze Kazuo, Naruko Takahiko, Sugioka Kenichi, Nakagawa Masashi, Yoshiyama Minoru, Inaba Mayumi, Ueda Makiko.
    • Organizer
      日本動脈硬化学会総会
    • Place of Presentation
      京王プラザホテル(東京都・新宿区)
    • Year and Date
      2014-07-10 – 2014-07-11
    • Related Report
      2014 Annual Research Report
  • [Presentation] 低酸素負荷におけるO-G1cNAc化タンパク質のオートファジーとアポトーシスへの影響2014

    • Author(s)
      渡辺 明, 佐々木 泉帆, 古川 裕一, 野村 篤生, 上橋 和佳, 加藤 隆児, 井尻 好雄, 中川 孝俊, 山口 雄大, 泉 康雄, 葭山 稔, 朝日 通雄, 林 哲也
    • Organizer
      日本循環制御医学会総会
    • Place of Presentation
      九州大学医学部 百年講堂(福岡県・福岡市)
    • Year and Date
      2014-07-04 – 2014-07-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 間歇的低酸素負荷がBio14.6心筋症ハムスターの心筋組織病変に与える影響2014

    • Author(s)
      銭 瑶子, 野村 篤生, 加藤 隆児, 安田 侑紀, 藤原 祐治, 松井 美佳, 室谷 美咲, 川上 淳, 井尻 好雄, 山口 雄大, 泉 康雄, 葭山 稔, 阪本 英二, 田中 一彦, 林 哲也
    • Organizer
      日本循環制御医学会総会
    • Place of Presentation
      九州大学医学部 百年講堂(福岡県・福岡市)
    • Year and Date
      2014-07-04 – 2014-07-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] フレーバーティにおける血管アンチエイジング効果2014

    • Author(s)
      前田 久美子, 島田 健永, 川崎 俊博, 宮花 礼子, 上原 久美子, 豊島 範子, 河野 靖, 久保 知一郎, 田口 晴之, 葭山 稔, 吉川 純一
    • Organizer
      日本抗加齢医学会総会
    • Place of Presentation
      大阪国際会議場(大阪府・大阪市)
    • Year and Date
      2014-06-06 – 2014-06-08
    • Related Report
      2014 Annual Research Report
  • [Presentation] Tolvaptan Reduces the Dose of Loop Diuretics and Improves Renal function in Patients with Congestive Heart Failure and Renal Dysfunction2014

    • Author(s)
      花谷彰久、葭山稔 他
    • Organizer
      第78回 日本循環器学会
    • Place of Presentation
      東京国際フォーラム
    • Related Report
      2013 Research-status Report
  • [Presentation] Reduction of Loop Diuretics by Tolvaptan Improves Renal Function in Patients with Congestive Heart Failure and Advanced Renal Dysfunction2014

    • Author(s)
      花谷彰久、葭山稔 他
    • Organizer
      第78回 日本循環器学会
    • Place of Presentation
      東京国際フォーラム
    • Related Report
      2013 Research-status Report
  • [Presentation] Repeated Remote Ischemic Conditioning Attenuates Left Ventricular Remodeling via Exosome-Mediated Intercellular Communication on Chronic Heart Failure after Myocardial Infarction2014

    • Author(s)
      山口雄大、葭山稔 他
    • Organizer
      第78回 日本循環器学会
    • Place of Presentation
      東京国際フォーラム
    • Related Report
      2013 Research-status Report
  • [Presentation] 急性心筋梗塞に対するインターロイキン11(IL-11)製剤を用いた心筋保護治療の臨床試験のためのプロトコール作成研究2013

    • Author(s)
      大和田 康子, 泉 康雄, 朝倉 正紀, 山本 晴子, 前田 真貴子, 葭山 稔, 藤尾 慈
    • Organizer
      第34回 日本臨床薬理学会
    • Place of Presentation
      東京国際フォーラム
    • Related Report
      2013 Research-status Report
  • [Presentation] 重症大動脈弁狭窄症における日間血圧変動と大動脈弓部プラークとの関連2013

    • Author(s)
      岩田 真一, 杉岡 憲一, 松村 嘉起, 藤田 澄吾子, 伊藤 朝広, 穂積 健之, 北田 諒子, 花谷 彰久, 葭山 稔
    • Organizer
      第61回 日本心臓病学会
    • Place of Presentation
      ホテル日航熊本
    • Related Report
      2013 Research-status Report
  • [Presentation] Dipperは本当にdipperか? 血圧日内変動パターンの変動性に関する検討2013

    • Author(s)
      岩田 真一, 泉 康雄, 花谷 彰久, 島田 健永, 葭山 稔
    • Organizer
      第36回 日本高血圧学会
    • Place of Presentation
      大阪国際会議場
    • Related Report
      2013 Research-status Report
  • [Presentation] Remote ischemic postconditioning improves coronary microcirculation in healthy subjects and in patients with heart failure.2012

    • Author(s)
      Kono Y, Fukuda S, Shimada K, Maeda K, Miyahana R, Kubo T, Jissho S, Taguchi H, Hanatani A, Yoshiyama M.
    • Organizer
      European society of cardiology congress 2012, Aug 25-29, 2012, Munich, Germany.
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2012 Research-status Report
  • [Presentation] Preliminary observations of passive exercise using whole body periodic acceleration on coronary microcirculation and glucose tolerance in patients with type 2 diabetes.2012

    • Author(s)
      Sakaguchi M, Fukuda S, Shimada K, Izumi Y, Izumiya Y, Nakamura Y, Nakanishi K, Otsuka K, Ogawa H, Fujita M, Yoshikawa J, Yoshiyama M.
    • Organizer
      European society of cardiology congress 2012, Aug 25-29, 2012, Munich, Germany.
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2012 Research-status Report
  • [Presentation] Persistent impairment of arterial stiffness is associated with future cardiovascular outcome in patients with coronary artery disease.2012

    • Author(s)
      Otsuka K, Fukuda S, Shimada K, Nakanishi K, Yoshikawa J, Yoshiyama M.
    • Organizer
      European society of cardiology congress 2012, Aug 25-29, 2012, Munich, Germany.
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2012 Research-status Report
  • [Presentation] Ring-like sign on coronary computed tomographic angiography is associated with near-future acute coronary syndrome in patients with coronary artery disease.2012

    • Author(s)
      Otsuka K, Fukuda S, Tanaka A, Nakanishi K, Sakamoto M, Taguchi H, Yoshikawa J, Shimada K, Yoshiyama M.
    • Organizer
      European society of cardiology congress 2012, Aug 25-29, 2012, Munich, Germany.
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2012 Research-status Report
  • [Presentation] Diagnostic accuracy and cost-effectiveness of pocket-sized transthoracic echocardiography.2012

    • Author(s)
      Kitada R, Fukuda S, Watanabe H, Oe H, Abe Y, Shimada K, Yoshiyama M, Ito H, Yoshikawa J.
    • Organizer
      European society of cardiology congress 2012, Aug 25-29, 2012, Munich, Germany.
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2012 Research-status Report
  • [Presentation] Low attenuation coronary plaque on multidetector computed tomography predicts three-year acute coronary syndrome events in patients with hypertension.2012

    • Author(s)
      Nakanishi K, Fukuda S, Shimada K, Ehara S, Inanami H, Matsumoto K, Taguchi H, Muro T, Yoshikawa J, Yoshiyama M.
    • Organizer
      European society of cardiology congress 2012, Aug 25-29, 2012, Munich, Germany.
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2012 Research-status Report
  • [Presentation] Peri-atrial epicardial adipose tissue is associated with new-onset non-valvular atrial fibrillation.2012

    • Author(s)
      Nakanishi K, Fukuda S, Tanaka A, Otsuka K, Sakamoto M, Taguchi H, Yoshikawa J, Shimada K, Yoshiyama M.
    • Organizer
      European society of cardiology congress 2012, Aug 25-29, 2012, Munich, Germany.
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2012 Research-status Report
  • [Presentation] Insulin resistance is associated with coronary plaque vulnerability: an Optical Coherence Tomography study.2012

    • Author(s)
      Tomokazu Iguchi, Takao Hasegawa, Kenichiro Otsuka, Satoshi Nishimura, Toru Kataoka, Shoichi Ehara, Akihisa Hanatani, Kenei Shimada, Minoru Yoshiyama.
    • Organizer
      European society of cardiology congress 2012, Aug 25-29, 2012, Munich, Germany.
    • Place of Presentation
      Munich, Germany.
    • Related Report
      2012 Research-status Report
  • [Presentation] Impact of increased epicardial adipose tissue volume on future acute coronary syndrome in patients with coronary artery disease.2012

    • Author(s)
      Nakanishi K, Fukuda S, Tanaka A, Otsuka K, Sakamoto M, Taguchi H, Yoshikawa J, Shimada K, Yoshiyama M.
    • Organizer
      American heart association scientific sessions 2012, Nov 3-7, 2012, Los Angeles, USA.
    • Place of Presentation
      Los Angeles, USA.
    • Related Report
      2012 Research-status Report
  • [Presentation] Persistent impairment of arterial stiffness is associated with future cardiovascular events in patients with hypertension; cardio-ankle vascular index study.2012

    • Author(s)
      Otsuka K, Fukuda S, Shimada K, Nakanishi K, Taguchi H, Yoshikawa J, Yoshiyama M.
    • Organizer
      American heart association scientific sessions 2012, Nov 3-7, 2012, Los Angeles, USA.
    • Place of Presentation
      Los Angeles, USA.
    • Related Report
      2012 Research-status Report
  • [Presentation] Percutaneous carbon dioxide treatment using a gas mist generator accelerates angiogenesis in the ischemic hindlimb.2012

    • Author(s)
      Yasukatsu Izumi, Takanori Yamazaki, Yasuhiro Nakamura, Takehiro Yamaguchi, Akihisa Hanatani, Kenei Shimada, Minoru Yoshiyama, Hiroshi Iwao.
    • Organizer
      American heart association scientific sessions 2012, Nov 3-7, 2012, Los Angeles, USA.
    • Place of Presentation
      Los Angeles, USA.
    • Related Report
      2012 Research-status Report
  • [Presentation] Percutaneous carbon dioxide mist treatment improves cardiac function after myocardial infarction in rats via nitric oxide activity.2012

    • Author(s)
      Takanori Yamazaki, Yasuhiro Nakamura, Yasukatsu Izumi, Takehiro Yamaguchi, Akihisa Hanatani, Kenei Shimada, Hiroshi Iwao, Minoru Yoshiyama.
    • Organizer
      American heart association scientific sessions 2012, Nov 3-7, 2012, Los Angeles, USA.
    • Place of Presentation
      Los Angeles, USA.
    • Related Report
      2012 Research-status Report
  • [Presentation] Vasopressin V2 receptor antagonist tolvaptan prevents the development of chronic heart failure via its anti-inflammatory and anti-fibrotic actions.2012

    • Author(s)
      Takanori Yamazaki, Yasuhiro Nakamura, Yasukatsu Izumi, Takehiro Yamaguchi, Akihisa Hanatani, Kenei Shimada, Hiroshi Iwao, Minoru Yoshiyama.
    • Organizer
      American heart association scientific sessions 2012, Nov 3-7, 2012, Los Angeles, USA.
    • Place of Presentation
      Los Angeles, USA.
    • Related Report
      2012 Research-status Report
  • [Presentation] II度以上の未治療高血圧症例に対する高用量ARB投与の有用性 ARB/CCB併用投与との比較検討2012

    • Author(s)
      中村 泰浩, 泉 康雄, 葭山 稔
    • Organizer
      日本高血圧学会臨床高血圧フォーラム
    • Place of Presentation
      大阪府豊中市
    • Related Report
      2012 Research-status Report
  • [Presentation] 健常人の血管内皮機能に対する遠隔虚血コンディショニングの効果の検討2012

    • Author(s)
      井口 朋和, 竹本 恭彦, 島田 健永, 大塚 憲一郎, 中西 弘毅, 松本 健嗣, 兵頭 永一, 花谷 彰久, 室生 卓, 葭山 稔
    • Organizer
      日本高血圧学会臨床高血圧フォーラム
    • Place of Presentation
      大阪府豊中市
    • Related Report
      2012 Research-status Report
  • [Presentation] 血管中内膜複合体厚と内皮依存性血管拡張反応の関連性 上腕動脈における同時測定による検討2012

    • Author(s)
      井口 朋和, 竹本 恭彦, 島田 健永, 花谷 彰久, 室生 卓, 葭山 稔
    • Organizer
      日本高血圧学会臨床高血圧フォーラム
    • Place of Presentation
      大阪府豊中市
    • Related Report
      2012 Research-status Report
  • [Presentation] 弁膜症の診断と治療 重症大動脈弁狭窄症における経食道心エコーによる大動脈弓部プラークの評価について2012

    • Author(s)
      杉岡 憲一, 穂積 健之, 松村 嘉起, 伊藤 朝広, 葭山 稔
    • Organizer
      日本超音波医学会学術集会
    • Place of Presentation
      東京都港区
    • Related Report
      2012 Research-status Report
  • [Presentation] 植込み型除細動器(ICD)によるshock直後の心室再分極の不均一性に対するNifekalantとAmiodaroneの効果2012

    • Author(s)
      前田 惠子, 高木 雅彦, 鈴木 健太郎, 辰巳 裕亮, 葭山 稔
    • Organizer
      日本不整脈学会学術大会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2012 Research-status Report
  • [Presentation] Brugada症候群におけるT-wave Alternansの日内変動についての検討2012

    • Author(s)
      鈴木 健太郎, 高木 雅彦, 前田 惠子, 辰己 裕亮, 葭山 稔
    • Organizer
      日本不整脈学会学術大会
    • Place of Presentation
      神奈川県横浜市
    • Related Report
      2012 Research-status Report
  • [Presentation] 健常人の血管内皮機能に対する遠隔虚血コンディショニングの効果の検討2012

    • Author(s)
      井口 朋和, 竹本 恭彦, 島田 健永, 松本 健嗣, 大塚 憲一郎, 中西 弘毅, 兵頭 永一, 花谷 彰久, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 心サルコイドーシスにおける心臓MRIガドリニウム遅延造影の特徴2012

    • Author(s)
      松本 健嗣, 江原 省一, 長谷川 隆生, 中田 真司, 大塚 憲一郎, 井口 朋和, 高木 雅彦, 花谷 彰久, 穂積 健之, 島田 健永, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 大動脈二尖弁の診断における経胸壁および経食道心エコーの相違 大動脈弁置換症例での検討2012

    • Author(s)
      武田 久輝, 室生 卓, 齋藤 聡男, 兵頭 永一, 江原 省一, 花谷 彰久, 島田 健永, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 光干渉断層像による冠動脈インターベンション後のFilter no-reflowの予測因子に関する検討2012

    • Author(s)
      井口 朋和, 長谷川 隆生, 松本 健嗣, 大塚 憲一郎, 中田 真司, 江原 省一, 花谷 彰久, 島田 健永, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 大動脈弁狭窄症の重症度指標を再考する2012

    • Author(s)
      齋藤 聡男, 室生 卓, 武田 久輝, 兵頭 永一, 花谷 彰久, 島田 健永, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 薬物加療が著効した右室二腔症の一例2012

    • Author(s)
      山下 智子, 松村 嘉起, 杉岡 憲一, 江原 省一, 花谷 彰久, 穂積 健之, 島田 健永, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 大動脈弁狭窄症における近位胸部大動脈の形態的変化についての検討 三尖弁と二尖弁大動脈弁狭窄症の比較2012

    • Author(s)
      藤田 澄吾子, 杉岡 憲一, 伊藤 朝広, 岩田 真一, 松村 嘉起, 穂積 健之, 末廣 茂文, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 大動脈弁狭窄症における冠動脈疾患合併と大動脈弓部プラークとの関連 経食道心エコー図による検討2012

    • Author(s)
      伊藤 朝広, 杉岡 憲一, 藤田 澄吾子, 岩田 真一, 松村 嘉起, 穂積 健之, 末廣 茂文, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 慢性腎臓病と大動脈プラークとの関連 近位胸部大動脈と遠位胸部大動脈との比較検討2012

    • Author(s)
      松村 嘉起, 杉岡 憲一, 藤田 澄吾子, 伊藤 朝広, 岩田 真一, 穂積 健之, 末廣 茂文, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 大動脈弁狭窄症を弁尖数から検討する 二尖弁と三尖弁の比較2012

    • Author(s)
      齋藤 聡男, 室生 卓, 武田 久輝, 兵頭 永一, 花谷 彰久, 島田 健永, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] たこつぼ型心筋症の重症化例を急性期心電図の特徴・心エコーの心機能指標で予測は可能か2012

    • Author(s)
      則岡 直樹, 太田 剛弘, 谷川 崇, 河合 慶介, 西山 裕善, 石川 世良, 白井 たから, 紙森 公雄, 柳 志郎, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 当院におけるトルバプタン使用例の検討2012

    • Author(s)
      白井 伸幸, 藤田 澄吾子, 長倉 俊樹, 村田 恵理子, 田中 秀昌, 河瀬 吉雄, 西本 正紀, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report
  • [Presentation] 循環器疾患とMRI Whole Heart Coronary T1-weighted Black Blood MRIを用いた冠動脈不安定プラーク描出の試み2012

    • Author(s)
      江原 省一, 長谷川 隆生, 中田 真司, 松本 健嗣, 井口 朋和, 大塚 憲一郎, 島田 健永, 葭山 稔
    • Organizer
      日本心臓病学会学術集会
    • Place of Presentation
      石川県金沢市
    • Related Report
      2012 Research-status Report

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi