Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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Outline of Final Research Achievements |
We evaluated the association between factors concerning mineral metabolism and those concerning diabetes by using cohorts of HD patients (1280 cases) and DM patients (408 cases). We found the influences of vitamin D on the progression of DM nephropathy and also found the effects of SNP(FokⅠVDR)and Copy Number Variation (CNV;UGT2B17)on the progression of DM nephropathy.Serum levels of FGF23, which suppress vitamin D activation showed a positive correlation with resistin concerning insulin resistance. Depending on our results, we hypothesize that mineral metabolism effects the progression of DM nephropathy.
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