| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
We investigated the resting state functional MRI data for more than 30 patients with various types of epilepsy (most cases were medically intractable patients). These data were compared with more than 300 normal controls’ data. We found that the patients with epilepsy tended to have larger functional connectivity than age-matched controls, especially around the epileptic focus estimated by electroencephalography. Brain functional network was stable when the patient’s symptom and medication did not change. After the surgery to resect epileptic focus, the patient’s brain network changed dramatically toward normal network. The results indicates that the brain network analysis in epilepsy is useful in diagnosis and treatment planning for the various types of epilepsy patients.
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