| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
We have established c-Myb reporter mice that can moniter the endogeous c-Myb protein. Utilizing the mice, we proved that c-Myb protein was able to control cell functions, especially HSCs, according to c-Myb expression levels. We have also confirmed the concepts of lineage-biased and dormant HSCs . We anticipate that these mice will become a new reserch tool that can efficiently isolate HSCs self-renewing from the embyonic to the adult stage.
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