mechanism of post zygotic chromosomal translocation

Research Project

Project/Area Number	24591524
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Pediatrics
Research Institution	Dokkyo Medical University
Principal Investigator	SAKAZUME satoru 獨協医科大学, 医学部, 講師 (70306174)
Co-Investigator(Kenkyū-buntansha)	久保田健夫山梨大学, 総合研究部, 教授 (70293511) 永井敏郎獨協医科大学, 医学部, 教授 (90296129)
Project Period (FY)	2012-04-01 – 2015-03-31
Project Status	Completed (Fiscal Year 2014)
Budget Amount *help	¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000) Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000) Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000) Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	染色体 / 転座 / 多型 / 受精 / 発達 / メチル化 / メカニズム / 成長
Outline of Final Research Achievements	We could not clarify the post zygotic trans location using rare chromosomal trans location. Unfortunately somatic cell hybrids were not obtained with conventional protocol. The break points were full of repeated elements and we could not find meaningful markers to know parental origins.

Report

(4 results)