Involvement of oxidative/nitrosative stress in the alteration of adipocyte-metabolisms induced by early nutritional disorder, and its control
| Project/Area Number |
24591525
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Showa University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 小児 / 栄養 / 肥満 / 脂質異常症 / 糖代謝異常 / 生活習慣病 / 脂肪細胞 / 酸化ストレス / 脂肪 / ストレス / 脂質異常 / 一酸化窒素 |
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| Outline of Final Research Achievements |
I have studied the oxidative / nitrosative stress and adipocytokine levels in cultured adipocytes and animal models with hyper-cytokinemia. Clinically, the effects of nutritional status in early infancy including neonatal period on future growth and the development of life-style related disease are investigated. Furthermore, new methods of evaluation of visceral fat accumulation, new markers of obesity, criteria of non-HDL-C, etc. have been studied by this grant. The obtained results are described in the text.
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Report
(4 results)
Research Products
(54 results)
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[Presentation] 小児の脂質異常症2014
Author(s)
土橋一重
Organizer
岩手内分泌・成長障害研究会
Place of Presentation
岩手
Year and Date
2014-11-21
Related Report
Invited
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