Acquisition process of sleep/wake rhythms assessed using non-invasive salivary markers and actigraphy
Project/Area Number |
24591533
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Pediatrics
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Research Institution | Kurume University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
IWATA Osuke 久留米大学, 小児科, 准教授 (30465710)
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Project Period (FY) |
2012-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
|
Keywords | 新生児 / 睡眠 / Actigraphy / コルチゾール / サーカディアンリズム / 認知障害 / 睡眠障害 |
Outline of Final Research Achievements |
It is largely unknown how foetal biological rhythms evolve into adult-type circadian rhythms, which are observed approximately 12 weeks of life. Using actigraphy and salivary biomarkers, we observed that diurnal rhythms, which mimic those of foetuses, can be observed even shortly after birth. In a large cohort of healthy one-month-old infants and their mothers, the infant’s nighttime sleep was dependent on both maternal life styles and intrinsic variables of the infant. Taken together, development of diurnal rhythms after birth is likely to be regulated by both extrinsic stimuli (e.g. maternal melatonin and lifestyle) and intrinsic programme (e.g. genetic factors).
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Report
(5 results)
Research Products
(72 results)
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[Journal Article] Infection surveillance after a natural disaster: lessons learnt from the Great East Japan Earthquake of 2011.2013
Author(s)
Iwata O, Oki T, Ishiki A, Shimanuki M, Fuchimukai T, Chosa T, Chida S, Nakamura Y, Shima H, Kanno M, Matsuishi T, Ishiki M, Urabe D.
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Journal Title
Bull World Health Organ.
Volume: 91(10)
Issue: 10
Pages: 784-9
DOI
Related Report
Peer Reviewed
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[Journal Article] Methyl-isobutyl amiloride reduces brain Lac/NAA, cell death and microglial activation in a perinatal asphyxia model.2013
Author(s)
Robertson NJ, Kato T, Bainbridge A, Chandrasekaran M, Iwata O, Kapetanakis A, Faulkner S, Cheong J, Iwata S, Hristova M, Cady E, Raivich G.
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Journal Title
J Neurochem.
Volume: 124(5)
Issue: 5
Pages: 645-57
DOI
Related Report
Peer Reviewed
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[Presentation] Oral feeding but not gastric tube feeding induces salivary cortisol elevation in newborn infants.2015
Author(s)
Saikusa M, Kinoshita M, Hirose A, Hara N, Tsuda K, Okamura H, Unno M, Kanda H, Iwata S, Urata C, Maeno M, Matsuishi ,Iwata O
Organizer
Pediatric Academic Societies
Place of Presentation
San Diego
Year and Date
2015-04-25
Related Report
Int'l Joint Research
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[Presentation] 唾液中コルチゾールの操作因子~経口摂取が持つ二面性の検討.2014
Author(s)
鍵山慶之,木下正啓,七種護,原直子,津田兼之介,海野光昭,田中祥一朗,岡田純一郎,久野正,廣瀬彰子,神田洋,前野泰樹,岩田欧介.
Organizer
第59回日本未熟児新生児学会学術集会
Place of Presentation
ひめぎんホール(愛媛県松山市)
Year and Date
2014-11-10 – 2014-11-12
Related Report
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[Presentation] 唾液マーカーによる生体リズムトレース2014
Author(s)
木下正啓,岡村尚昌,鍵山慶之,浦田千穂子,津田兼之介,海野光昭,廣瀬彰子,岩田幸子,松石豊次郎,岩田欧介.
Organizer
第3回日本発達神経科学学会
Place of Presentation
東京大学 武田ホール(東京)
Year and Date
2014-10-18 – 2014-10-19
Related Report
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[Presentation] 産後1か月時の母子睡眠影響因子の検討2014
Author(s)
岩田欧介,藤田史恵,諸隈誠一,木下正啓,海野光昭,鍵山慶之,廣瀬彰子,岩田幸子, 松石豊次郎.
Organizer
第3回日本発達神経科学学会
Place of Presentation
東京大学 武田ホール(東京)
Year and Date
2014-10-18 – 2014-10-19
Related Report
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[Presentation] 唾液中コルチゾールの影響因子の検討:経管栄養と哺乳.2014
Author(s)
木下正啓,七種護,原直子,津田兼之介,海野光昭,才津宏樹,田中祥一朗,岡田純一郎,久野正,廣瀬彰子,神田洋,前野泰樹,岩田欧介.
Organizer
第50回日本周産期・新生児医学会総会
Place of Presentation
シェラトン・グランデ・トーキョーベイ・ホテル(千葉県浦安市)
Year and Date
2014-07-13 – 2014-07-15
Related Report
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[Presentation] Oral feeding but not gastric tube feeding induces salivary cortisol elevation in newborn infants.2014
Author(s)
Hirose A, Sakamoto H, Hara N, Kinoshita M, Tsuda K, Okamura H, Unno M, Kanda H, Iwata S, Urata C, Maeno Y, Matsuishi T and Iwata O.
Organizer
Joint Meeting of Pediatric Academic Societies and Asian Society for Pediatric Research.
Place of Presentation
Vancouver (Canada)
Year and Date
2014-05-03 – 2014-05-06
Related Report
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[Presentation] 小児救命集中治療領域における多施設共同研究と症例集約の重要性2012
Author(s)
清水 直樹, 六車 崇, 伊藤 友弥, 新津 健裕, 齊藤 修, 植田 育也, 志馬 伸朗, 新田 雅彦, 太田 邦雄, 岩田 欧介, 日本集中治療医学会小児集中治療委員会
Organizer
第115回日本小児科学会学術集会
Place of Presentation
福岡国際会議場
Related Report
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[Presentation] 脳室腹腔内シャント術を必要としなかった急速進行性出血後水頭症の2症例2012
Author(s)
牛嶋 規久美, 木下 正啓, 田中 祥一朗, 才津 宏樹, 海野 光昭, 岡田 純一郎, 久野 正, 岩田 幸子, 神田 洋, 前野 泰樹, 岩田 欧介
Organizer
第48回日本周産期・新生児医学会学術集会
Place of Presentation
大宮ソニックシティー
Related Report
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[Presentation] 晩期循環不全の中期予後の検討2012
Author(s)
神田 洋, 木下 正啓, 海野 光昭, 才津 宏樹, 岡田 純一郎, 久野 正, 田中 祥一朗, 岩田 幸子, 前野 泰樹, 岩田 欧介
Organizer
第48回日本周産期・新生児医学会学術集会
Place of Presentation
大宮ソニックシティー
Related Report
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[Presentation] 大動脈および肺動脈の拡張期血流波形による簡便な胎児不整脈診断法2012
Author(s)
前野 泰樹, 漢 伸彦, 堀之内 崇士, 上妻 友隆, 田中 祥一朗, 才津 宏樹, 海野 光昭, 神田 洋, 岩田 欧介, 堀 大蔵, 嘉村 敏治, 松石 豊次郎
Organizer
第48回日本周産期・新生児医学会学術集会
Place of Presentation
大宮ソニックシティー
Related Report
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