| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
Short QT Syndrome (SQTS) is characterized by a short QT interval (QTI) and is a cause of sudden death at premature age. QTI were measured in 13948 subjects 12-13 years old in a school-based ECG screening program. 30 subjects with QTI below the 0.25th percentile of the total subjects, were enrolled. We conducted further examination. The mean follow-up period was 2.1 years. 12 of 30 met the SQTS diagnostic criterion proposed in 2013. 5 subjects had a family history of premature sudden death. One was observed with ventricular tachycardia. 3 had an episode of syncope during follow-up period. Among them, one was diagnosed with epilepsy, while the others were diagnosed with neurally mediated syncope. 7 of 12 who met the SQTS diagnostic criterion were observed with normal QTI during follow-up period. Genetic analysis for SQTS genes, did not show any mutations in two subjects. The criteria might overdiagnose SQTS in adolescent population.
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