Effect of cognitive rehabilitation for early schizophrenia patients on cognitive function and brain structures
Project/Area Number |
24591694
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Psychiatric science
|
Research Institution | Tohoku University |
Principal Investigator |
HIROO Matsuoka 東北大学, 医学(系)研究科(研究院), 教授 (00173815)
|
Co-Investigator(Kenkyū-buntansha) |
MATSUMOTO Kazunori 東北大学, 医学系研究科, 准教授 (40301056)
TAKI Yasuyuki 東北大学, 加齢医学研究所, 教授 (10375115)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 認知リハビリテーション / 精神医学 / 統合失調症 / 認知機能 |
Outline of Final Research Achievements |
Cognitive impairment is one of the core symptoms of schizophrenia that significantly influences patients’ social function. Cognitive remediation, of which a main component is repetitive cognitive training, is a promising approach for this impairment. In this study, we used brain training games as a cognitive training program. In addition to measuring the change in cognitive performance from pre- to post-intervention, we investigated the influence of cognitive training on gray matter structures. An 8-week intervention revealed that cognitive training using brain training games significantly improved patients’ processing speed and executive function compared to visuospatial puzzle games. In addition, the improved cognitive performance was accompanied by regional gray matter volume changes. These findings suggest that cognitive training not only influences the performance on cognitive measures, but also patients’ neural structures.
|
Report
(4 results)
Research Products
(1 results)
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[Presentation] Applying a cognitive training program using a brain training game to patients with schizophrenia: study protocol for a randomized trial.2014
Author(s)
Kunio Iizuka, Kazunori Matsumoto, Rui Nouchi, Yasuyuki Taki, Hikaru Takeuchi, Takayuki Nozawa, Hiroshi Hashizume, Ryoichi Yokoyama, Yukako Sasaki, Chika Obara, Hiroo Matsuoka, Ryuta Kawashima
Organizer
9th International Conference on Early Psychosis
Place of Presentation
京王プラザホテル(東京)
Year and Date
2014-11-17 – 2014-11-19
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