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Study on the global clinical accessment of efficacy of anti-dementia drugs

Research Project

Project/Area Number 24591717
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Psychiatric science
Research InstitutionKagawa University

Principal Investigator

NAKAMURA Yu  香川大学, 医学部, 教授 (70291440)

Co-Investigator(Kenkyū-buntansha) SHINNO Hideto  香川大学, 医学部, 客員教授 (10393430)
IMAI Hideki  香川大学, 医学部附属病院, 助教 (00558512)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords認知症 / ADL / 全般臨床評価 / 抗認知症薬 / 介護者 / 臨床評価
Outline of Final Research Achievements

To access the change of the clinical symptoms of AD patients, it is necessary to obtain much information of good quality from their caregivers. However, the information obtained from a single family caregiver has many problems. Then, we investigated where those problems are laying. It is concluded that it is necessary to get more information not only from a major caregiver but also from the other caregivers such as other family members and professional caregivers on the ADLs such as bathig, watching, excretion, short trip, dental care, dressing, taking medicines, leisure and house keeping.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2015 2014 2013 2012

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (3 results)

  • [Journal Article] Efficacy and safety of mamantine in patients with maderate-to-severe Aizheimer's disease:results of a pooled analysis of two randomized,doubie-blind,placebo-controlled trials in Japan2014

    • Author(s)
      Yu Nakamara,Shin Kitamura,Akira Homma,Kazuhiro Shiosakai & Daiju Matsui
    • Journal Title

      Expert Opin.Pharmacother

      Volume: 15(7) Issue: 7 Pages: 1744-7666

    • DOI

      10.1517/14656566.2014.902446

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pentylentetrazole-induced loss of blood-brain barrier integrity involves excess nitric oxide generation by neuronal nitric oxide synthase.2013

    • Author(s)
      Danjo S, Ishihara Y, Watanabe M, Nakamura Y, Itoh K.
    • Journal Title

      Brain Res

      Volume: 12 Pages: 44-53

    • DOI

      10.1016/j.brainres.2013.06.043

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] A patient with type II citrullinemia who developed refractory complex seizure. Gen Hosp Psychiatry.2013

    • Author(s)
      Sakamoto S, Nakamura Y, et al.
    • Journal Title

      Disease Patients. Dement Geriatr Cogn Dis Extra.

      Volume: 35(1) Issue: 1 Pages: 103-103

    • DOI

      10.1016/j.genhosppsych.2012.03.019

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] CIBIC Plus-J Assessment Using a Videotaped Method in Alzheimer's.2012

    • Author(s)
      Nakamura Y, et al.
    • Journal Title

      Disease Patients. Dement Geriatr Cogn Dis Extra.

      Volume: 2(1) Issue: 1 Pages: 271-7

    • DOI

      10.1159/000339953

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] Prescribing status of psychotropic drugs for the treatment of BPSD; A survey for primary care physicians and dementia specialists in Japan.2015

    • Author(s)
      Norifumi TSUNO, Yu NAKAMURA, Akira HOMMA
    • Organizer
      AD/PD 2015 The 12th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders.
    • Place of Presentation
      France, Nice
    • Year and Date
      2015-03-18 – 2015-03-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 当院の緩和ケアにおける抗うつ薬の使用経験2014

    • Author(s)
      石川 一朗,上野 美幸,中條 浩介,新野 秀人,中村 祐
    • Organizer
      第11回日本うつ病学会
    • Place of Presentation
      広島
    • Year and Date
      2014-07-18 – 2014-07-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Analysis of polysomnography variables on the prediction of conversion from mild cognitive impairment to Alzheimer’s disease2014

    • Author(s)
      Hideto Shinno, Ichiro Ishikawa, Nobuo Ando, and Yu Nakamura
    • Organizer
      FENS 2014 9th FENS Forum of Neuroscience
    • Place of Presentation
      Italy, Milan
    • Year and Date
      2014-07-05 – 2014-07-09
    • Related Report
      2014 Annual Research Report

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Published: 2013-05-31   Modified: 2019-07-29  

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