Investigation about an effect of metabolic syndrome on onset of subjective cognitive impairment: cohort study in Japanese community-dwelling older people
Project/Area Number |
24591726
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Psychiatric science
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Research Institution | Nara Medical University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
OKAMOTO NOZOMI 奈良県立医科大学, 医学部, 准教授 (70364057)
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Project Period (FY) |
2012-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
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Keywords | 主観的認知障害 / 地域在住高齢者 / 経度認知障害 / 認知症 / 社会的サポート / メタボリック症候群 / アポリポプロテインE4 / 軽度認知障害 / 認知機能低下 / 抑うつ状態 / 残存歯数 |
Outline of Final Research Achievements |
Japanese community-dwelling older people (1316 men, 1318 women) without depression and cognitive decline, aged more than 65 years old, were followed up for 5 years. In baseline examination (2007-2008), the prevalence of subjective memory impairment (SCI) was 73.9%. Five years later, 45.8% had still suffered from SCI, 28.4% had improved normally, and 7.8% had been aware of SCI. Of cognitively normal people in the baseline, 9.5% had declined to MCI and 4.5% to dementia (MMSE < 24).SCI and metabolic syndrome did not affect cognitive decline during 5 year follow-up interval. To protect cognitive decline might live independently under less social support.
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Report
(5 results)
Research Products
(15 results)
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[Journal Article] Association between depressive symptoms and metabolic syndrome in Japanese community-dwelling older people: a cross-sectional analysis from the baseline results of the Fujiwara-kyo prospective cohort study.2013
Author(s)
Morikawa M, Okamoto N, Kiuchi K, Tomioka K, Iwamoto J, Harano A, Saeki K, Fukusumi M, Hashimoto K, Amano N, Hazaki K, Yanagi M, Iki M, Yamada F, Kishimoto T, Kurumatani N.
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Journal Title
Int J Geriatr Psychiatry
Volume: 28
Issue: 12
Pages: 1251-1259
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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