Follow-up study on the non-transient cases with At-risk mental state (ARMS)
| Project/Area Number |
24591732
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Toho University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TSUJINO Naohisa 東邦大学, 医学部, 講師 (00459778)
NEMOTO Takahiro 東邦大学, 医学部, 准教授 (20296693)
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| Research Collaborator |
INOUE Naomi
YOROZUYA Yuko
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 精神病発症危険状態 / 精神病発症超ハイリスク / 移行例・非移行例 / 統合失調症 / 早期介入 / 精神病 / ARMS |
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| Outline of Final Research Achievements |
Objectives: To observe trajectories of symptoms and psychosocial functioning in patients at ultra-high risk (UHR) for psychosis as well as to investigate the psychosocial predictors of transition to psychosis.
Method: Twenty-two prospectively identified patients fulfilling UHR criteria were followed in one-year longitudinal study. Symptoms and psychosocial functioning were measured at the baseline and after one year follow-up.Result: Among the 15 patients who underwent follow-up evaluation, 6 subjects had converted to full-blown psychosis at one year, and 9 had not. There was a tendency for non-converters to have lower social-functioning at their baseline than the converters.Conclusion: The study suggests the need for treatment targeting not only the prevention of developing psychosis but also targeting the recovery of social-functioning. Further investigation of UHR patients should be considered with longer follow up duration.
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Report
(4 results)
Research Products
(31 results)
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[Presentation] Early intervention for ultra-high risk youth in Japan: Clinical practice in three leading centres.2014
Author(s)
Masahiro Katsura, Naohisa Tsujino, Shimako Nishiyama, Yoko Baba, Noriyuki Ohmuro, Yuko Higuchi, Tsutomu Takahashi, Takahiro Nemoto, Hiroo Matsuoka, Michio Suzuki, Masafumi Mizuno, Kazunori Matsumoto
Organizer
9th International Conference on Early Psychosis
Place of Presentation
Keio Plaza Hotel, Tokyo, Japan
Year and Date
2014-11-18
Related Report
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[Presentation] Influence of Expressed Emotion on clinical status of At-Risk Mental State.2014
Author(s)
Funatogawa T, Nemoto T, Saito J, Baba Y, Tobe M, Hasuya H, Takeshi K, Yamaguchi T, Katagiri N, Tsujino N, Niimura H, Mizuno M
Organizer
9th International Conference on Early Psychosis.
Place of Presentation
Keio Plaza Hotel, Tokyo, Japan
Year and Date
2014-11-17
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[Presentation] Social anxiety as a treatment target to improve social adjustment and quality of life in schizophrenia.2014
Author(s)
Sayaka Aikawa, Takahiro Nemoto, Naohisa Tsujino, Yoko Baba, Yuko Yorozuya, Miki Tobe, Kiyoaki Takeshi, Taiju Yamaguchi, Naoyuki Katagiri, Masafumi Mizuno.
Organizer
Schizophrenia International Research Society 2014.
Place of Presentation
Florence, Italy
Year and Date
2014-04-07
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[Presentation] Efficacy of a comprehensive treatment center for early psychosis in Japan: A 1-year follow-up study.
Author(s)
T Nemoto, K Takeshi, T Funatogawa, M Tobe, Y Saito, M Takahashi, E Moritsugu, J Saito, N Katagiri, H Niimura, N Tsujino, M Mizuno
Organizer
8th International Conference on Early Psychosis
Place of Presentation
San Francisco, USA
Related Report
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[Book] 統合失調症第３巻2012
Author(s)
舩渡川智之、根本隆洋、武士清昭、水野雅文
Total Pages
115
Publisher
医薬ジャーナル社
Related Report
