| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Outline of Final Research Achievements |
We investigated acoustic startle response (ASR), and acoustic information processing by electroencephalogram and magnetoencephalography in children with and without autism spectrum disorders (ASD). Compared to controls, children with ASD revealed significantly larger startle magnitude to weak stimuli and more prolonged peak startle latency. Significant negative association was found between duration-deviant Mismatch negativity current density of right inferior frontal gyrus and total score of Social Responsive Scale. Increased gamma oscillation power dominant around right auditory cortex was only found in non-ASD children with low autistic traits. Our results suggest that comprehensive investigation of ASR and neurophysiological index using simple acoustic stimuli might increase understanding of atypical acoustic information processing underlying ASD.
|
