| Project/Area Number |
24591751
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | University of Fukui |
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Principal Investigator |
MORI Tetsuya 福井大学, 高エネルギー医学研究センター, 助教 (40397287)
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| Co-Investigator(Renkei-kenkyūsha) |
KIYONO Yasushi 福井大学, 高エネルギー医学研究センター, 教授 (50305603)
OKAZAWA Hidehiko 福井大学, 高エネルギー医学研究センター, 教授 (50360813)
FUJIBAYASHI Yasuhisa 放射線医学総合研究所, 分子イメージング研究センター, センター長 (50165411)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | PET薬剤 / 自動合成 / 放射性薬剤 / 自動合成システム / エストロゲンレセプター / アンドロゲンレセプター / 薬剤開発 / 放射性診断薬 / PET |
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| Outline of Final Research Achievements |
Automated synthesizer is necessary for translational research of PET tracers because it has advantages such as reproducibility production and workers exposure reduction. Most of the synthesizer is a high performance for clinical use, but is expensive. Therefore, we have designed a flexible module system at low cost for preclinical studies using commercially available servomotors for hobby robot kits. The system was realized to control plastic three-way valves, plastic syringes and I/O units for external devises. The layout of the modules were optimized for the synthesis of target tracers, and accomplished 4 tracers production. This flexible system can modify layout to suit the needs or preferences of the user. Therefore, the convenient system may help the research of the PET tracer development.
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