Establishment of excretory MR pancreatography using 3Tesla MR and initial clinical application

• Project/Area Number: 24591754
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Nagoya University
• Principal Investigator: Suzuki Kojiro 名古屋大学, 医学(系)研究科(研究院), 准教授 (60378148)
• Co-Investigator(Kenkyū-buntansha): NAGANAWA Shinji 名古屋大学, 医学系研究科, 教授 (50242863)
• Co-Investigator(Renkei-kenkyūsha): TAKADA Akira 名古屋大学, 医学部附属病院, 助教 (70584861)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: 画像診断 / MRI / 膵臓 / 膵管造影 / 膵管撮影 / 画像診断学

Outline of Final Research Achievements

We established the scanning method of excretory MR pancreatography using 3Tesla MR. MR pancreatography with heavily T2-weighted three-dimensional fluid-attenuated inversion recovery (hT2W-3D-FLAIR) could visualize the main pancreatic duct after intravenous gadolinium-based contrast material administration. We evaluated hT2W-3D-FLAIR pancreatography comparing with usual MR pancreatography in 8 healthy volunteers. Optimal delay time was 2 hours after contrast material administration. And the visualization of the main pancreatic duct was most superior in the pancreatic body.

Research Products

• [Journal Article] Contrast-enhanced Magnetic Resonance Pancreatography with Gadoteridol by Heavily T2-weighted three-dimensional fluid-attenuated inversion recovery: Preliminary Results in Healthy Subjects (2016)
  • Author(s): Kojiro Suzuki, Shinji Naganawa, Naohiro Furuhashi, Masahiro Yamazaki, Hiroshi Ogawa, Hisashi Kawai
  • Journal Title: Nagoya Journal of Medical Science Volume: in press
  • NAID: 120005756084
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] Excretory MR pancreatography after intravenous administration of gadoteridol: preliminary results in eight healthy volunteers (2014)
  • Author(s): Kojiro Suzuki, Shinji Naganawa, Hirofumi Furuhashi, Ryota Hyodo, Masahiro Yamazaki
  • Organizer: European Congress of Radiology
  • Place of Presentation: Vienna, Austria