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Diagnosis and risk stratification of breast lesions using DWI and automated color-coding

Research Project

Project/Area Number 24591756
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionKyoto University

Principal Investigator

KATAOKA Masako  京都大学, 医学(系)研究科(研究院), 助教 (10611577)

Research Collaborator KANAO Shotaro  , 放射線部, 助教
IIMA Mami  , 画像診断・核医学講座, 学術振興会特別研究員
ONISHI Natsuko  , 画像診断・核医学講座
KAWAI Makiko  , 画像診断・核医学講座
OHASHI Akane  , 画像診断・核医学講座
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
KeywordsMRI / 拡散強調画像 / 乳癌 / ADC値 / 乳房 / DWI / 診断 / 乳腺 / カラーマップ
Outline of Final Research Achievements

We have published a paper showing the usefulness of DWI-derived parameters including ADC, IVIM and kurtosis in diagnosing malignant /benign breast lesions. We also established the computer program displaying each parameters and risk scores per each pixel fused with conventional MR image, presenting the utility of these color map in clinical diagnosis at the international meeting. In summary DWI-derived parameters and their color mapping are suggested as a useful tool in diagnosing and evaluating breast lesions.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (12 results)

All 2015 2014 2013

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Acknowledgement Compliant: 1 results) Presentation (9 results) (of which Invited: 1 results)

  • [Journal Article] Quantitative Non-Gaussian Diffusion and Intravoxel Incoherent Motion Magnetic Resonance Imaging: Differentiation of Malignant and Benign Breast Lesions.2015

    • Author(s)
      Iima M, Yano K, Kataoka M, Umehana M, Murata K, Kanao S, Togashi K, Le Bihan D.
    • Journal Title

      Investigative Radiology

      Volume: 50 Issue: 4 Pages: 205-211

    • DOI

      10.1097/rli.0000000000000094

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Detection of axillary lymph node metastasis with diffusion-weighted MR imaging2014

    • Author(s)
      Iima M, Kataoka M, Okumura R, Togashi K.
    • Journal Title

      Clinical Imaging

      Volume: 38 Issue: 5 Pages: 633-636

    • DOI

      10.1016/j.clinimag.2014.04.016

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Apparent diffusion coefficient as a potential surrogate marker for Ki-67 index in mucinous breast carcinoma.2014

    • Author(s)
      Onishi N, Kanao S, Kataoka M, Iima M, Sakaguchi R, Kawai M, Kataoka T, Mikami Y, Toi M, Togashi K., et al.
    • Journal Title

      Journal of Magnetic Resonance Imaging.

      Volume: (印刷中) Issue: 3 Pages: 24615-24615

    • DOI

      10.1002/jmri.24615

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Non-Gaussian Diffusion MRI and Dynamic Contrast - Enhanced MRI in Evaluation of Early Treatment Effects During Neoadjuvant Chemotherapy for Breast Cancer2014

    • Author(s)
      Iima M, Kataoka M, Kanao S, Yano K, Umehana M, Ohashi A, Kawai M, Onishi N, Togashi K, Le Bihan D
    • Organizer
      The 15th Asian Oceania Congress of Radiology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2014-09-24 – 2014-09-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] IVIMと非ガウス拡散MRI - 癌診断におけるバイオマーカーとし ての可能性2014

    • Author(s)
      飯間麻美, デニスルビアン , 片岡正子 ,富樫かおり
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-18 – 2014-09-20
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Computer-assisted diagnosis of breast lesions based on IVIM and non Gaussian diffusion MRI2014

    • Author(s)
      Iima M, Kataoka M, Umehana M, Nakanishi Y, Ito T, Yano K, Kanao S, Togashi K. Le Bihan D
    • Organizer
      The 22nd Annual Scientific Meeting and Exhibition of The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2014-05-10 – 2014-05-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] Apparent diffusion coefficient as a potential surrogate marker for Ki-67 index in mucinous breast carcinoma: comparison with invasive carcinoma of no special type2014

    • Author(s)
      Onishi N, Kanao S, Kataoka M, iima M, Sakaguchi R, kawai M, Kataoka T, Mikami Y, Toi M, Togashi K.
    • Organizer
      The 22nd Annual Scientific Meeting and Exhibition of The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2014-05-10 – 2014-05-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] Computer-aided IVIM/Kurtosis Diffusion MRI for breast lesions: comparison with BIRADS MRI categories2014

    • Author(s)
      Iima M, Kataoka M, Nakanishi Y, Umehana M, Imakita T, Ito, Yano K, Kanao S, Togashi K, Le Bihan D
    • Organizer
      European Congress of Radiology Vienna, 2014, March 6-10
    • Place of Presentation
      Vienna
    • Related Report
      2013 Research-status Report
  • [Presentation] Computer-assisted diagnosis of breast lesions based on IVIM and non Gaussian diffusion MRI2014

    • Author(s)
      Iima M, Kataoka M, Umehana M, Nakanishi Y, Ito T, Yano K, Kanao S, Togashi K. Le Bihan D.
    • Organizer
      The 22 Annual Scientific Meeting and Exhibition of The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Milan, Italy
    • Related Report
      2013 Research-status Report
  • [Presentation] Apparent diffusion coefficient as a potential surrogate marker for Ki-67 index in mucinous breast carcinoma: comparison with invasive carcinoma of no special type2014

    • Author(s)
      Onishi N, Kanao S, Kataoka M, iima M, Sakaguchi R, kawai M, Kataoka T R, Mikami Y, Toi M, Togashi K
    • Organizer
      The 22 Annual Scientific Meeting and Exhibition of The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Milan, Italy
    • Related Report
      2013 Research-status Report
  • [Presentation] Potential of perfusion imaging with IVIM MRI in breast cancer2013

    • Author(s)
      Iima M, Kataoka M, Le Bihan D, Umehana M, Imakita T, Nakagawa M, Kanao S, Yano K, Feiweier T, Togashi K
    • Organizer
      The 21th Annual Scientific Meeting and Exhibition of The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Salt lake City, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Potential of perfusion imaging with IVIM MRI in breast cancer2013

    • Author(s)
      Iima M, Kataoka M, Le Bihan D, Umehana M, Imakita T, Nakagawa M, Kanao S, Yano K, Feiweier T, Togashi K
    • Organizer
      The 21th Annual Scientific Meeting and Exhibition of The International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Salt Lake City, Utah, USA
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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