Optimization and clinical application of double IR sequence for CNS diseases
Project/Area Number |
24591757
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Radiation science
|
Research Institution | Kyoto University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
OKADA Tomohisa 京都大学, 医学研究科, 講師 (30321607)
YAMAMOTO Akira 京都大学, 医学研究科, 助教 (60525567)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | MRI / てんかん / FDG-PET |
Outline of Final Research Achievements |
Double IR sequence was optimized and tested on 3T MR. Double IR was the most sensitive sequence for detecting seizure focus laterality in temporal lobe epilepsy among the 2D and 3D sequences tested. Double IR was also shown to have high-detection ability for seizure focus laterality in temporal lobe epilepsy using VBA compared with FDG-PET. An important finding was that the laterality of increased signal intensity areas in the white matter on double IR located concordantly with the hypometabolic areas on FDG-PET.
|
Report
(4 results)
Research Products
(8 results)
-
-
[Journal Article] Evaluation of Focus Laterality in Temporal Lobe Epilepsy: A Quantitative Study Comparing Double Inversion-Recovery MR Imaging at 3T with FDG-PET.2013
Author(s)
Morimoto E, Okada T, Kanagaki M, Yamamoto A, Fushimi Y, Matsumoto R, Takaya S, Ikeda A, Kunieda T, Kikuchi T, Paul D, Miyamoto S, Takahashi R, Togashi K.
-
Journal Title
Epilepsia
Volume: 54
Issue: 12
Pages: 2174-83
DOI
Related Report
Peer Reviewed
-
-
-
[Journal Article] Anterior temporal lobe white matter abnormal signal (ATLAS) as an indicator of seizure focus laterality in temporal lobe epilepsy: comparison of double inversion-recovery, FLAIR and T2W MR imaging2012
Author(s)
Morimoto E, Kanagaki M, Okada T, Yamamoto A, Mori N, Matsumoto R, Ikeda A, Mikuni N, Kunieda T, Paul D, Miyamoto S, Takahashi R, Togashi K
-
Journal Title
Eur Radiol
Volume: 23
Issue: 1
Pages: 3-11
DOI
Related Report
Peer Reviewed
-
-
[Presentation] Evaluation of Focus Laterality in Temporal Lobe Epilepsy: A Quantitative Study Comparing Double Inversion-recovery MR Imaging at 3T with FDG-PET2013
Author(s)
Morimoto E, Okada T, Kanagaki M, Yamamoto A, Fushimi Y, Matsumoto R, Takaya S, Ikeda A, Kunieda T, Kikuchi T, Paul D, Miyamoto S, Takahashi R, Togashi K
Organizer
Radiological Society of North America (RSNA) 99th Scientific Assembly and Annual Meeting
Place of Presentation
Chicago, USA
Related Report
-