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Prognosis prediction of gastrointestinal cancers based on intratumoral blood flow using contrast enhanced CT

Research Project

Project/Area Number 24591771
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionKyushu University (2012, 2014)
National Hospital Organization, Kyushu Cancer Center (2013)

Principal Investigator

KOMORI Masahiro  九州大学, 医学(系)研究科(研究院), 研究員 (90529819)

Co-Investigator(Kenkyū-buntansha) TSURUMARU Daisuke  九州大学, 大学病院, 助教 (90419565)
ASAYAMA Yoshiki  九州大学, 大学病院, 助教 (40380414)
MIYASAKA Mitsutoshi  九州大学, 大学病院, 助教 (10457434)
NISHIMUTA Yusuke  九州大学, 大学病院, 医員 (10635220)
HONDA Hiroshi  九州大学, 医学研究院, 教授 (90145433)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords胃癌 / 大腸癌 / マルチスライスCT / 高分解能CT / 進行大腸癌 / 動脈性血行 / MDCT / 進行胃癌
Outline of Final Research Achievements

In this study, we examined relationship between intratumoral blood flow and prognostic factors of gastric and colorectal cancer using a multi-slice CT. We treated pathological proven gastric cancers (n=21) and colorectal cancers (n=33). We used multiphasic contrast-enhanced CT (320 detector) for preoperative workup. We performed qualitative and quantitative analyses and evaluated the relationship between the imaging features and prognostic factors of gastric and colorectal cancers. There was no significant difference between enhancement pattern and recurrence of gastric cancers. Colorectal cancers with poor arterial blood flow (contrast enhancement) had association with possibility of high grade pathological malignancy.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (10 results)

All 2015 2014 2013 Other

All Journal Article (6 results) (of which Peer Reviewed: 3 results) Presentation (4 results)

  • [Journal Article] 消化管がん診療の新しいエビデンス 微小癌の診断限界 大腸癌2014

    • Author(s)
      上田 真信, 井野 彰浩, 古森 正宏, 奥島 一洋
    • Journal Title

      臨床と研究

      Volume: 92 Pages: 192-196

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 悪性リンパ腫の診断と治療 鑑別診断に重点をおいて 消化管 胃・十二指腸・小腸・大腸2014

    • Author(s)
      鶴丸 大介, 西牟田 雄祐, 宮坂 光俊, 川波 哲, 浅山 良樹, 西江 昭弘, 平賀 聖久, 本岡 愼, 本田 浩
    • Journal Title

      画像診断

      Volume: 59 Pages: 1466-1474

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 内視鏡的に切除したブルンネル腺過形成の1例2013

    • Author(s)
      高津憲之、古森正宏
    • Journal Title

      臨床放射線

      Volume: 58 Pages: 1887-1891

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Extent of arterial tumor enhancement measured with preoperative MDCT gastrography is a prognostic factor in advanced gastric cancer after curative resection2013

    • Author(s)
      M Komori, Y Asayama, N Fujita
    • Journal Title

      American Journal of Roentgenology

      Volume: 201

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Prediction of intraoperative bleeding during endoscopic treatment in patients with early gastric cancers: utility of contrast-enhanced MDCT gastrography and the wall-carving image technique2013

    • Author(s)
      D Tsurumaru, S Kawanami, M Komori
    • Journal Title

      Japanese Journal of Radiology

      Volume: 31 Pages: 237-242

    • NAID

      210000178481

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] 悪性腫瘍の病期診断 ─治療法と予後の分岐点を見極める─2013

    • Author(s)
      西牟田雄祐,古森正宏,鶴丸大介
    • Journal Title

      画像診断

      Volume: 33 Pages: 85-97

    • Related Report
      2012 Research-status Report
  • [Presentation] Dynamic Contrast-Enhanced CT of Gastric Cancers: Relationship between Enhancement Pattern and Histological Type2015

    • Author(s)
      Daisuke Tsurumaru, Mitsutoshi Miyasaka, Yusuke Nishimuta, Satoshi Kawanami, Yoshiki Asayama, Akihiro Nishie, Hiroshi Honda
    • Organizer
      ECR 2015
    • Place of Presentation
      Vienna
    • Year and Date
      2015-03-06 – 2015-03-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] Arterial contrast enhancement degree on CT-gastrography utilizing a newly developed volume rendering in early gastric cancer: Correlation with histologic features.2013

    • Author(s)
      M Komori
    • Organizer
      American Roentgen Ray Society Annual Meeting
    • Place of Presentation
      Washington DC, United States
    • Related Report
      2013 Research-status Report
  • [Presentation] Contrast-enhanced CT-gastroscopy for early gastric cancer : Imaging features and prediction of malignancy2013

    • Author(s)
      M. Komori, Y. Asayama, Y. Nishimuta
    • Organizer
      European Congress of Radiology
    • Place of Presentation
      Vienna
    • Related Report
      2012 Research-status Report
  • [Presentation] 精検フィルム検討会における検診発見胃癌の見直し診断の検討

    • Author(s)
      古森 正宏
    • Organizer
      第42 回日本消化器がん検診学会九州地方会
    • Place of Presentation
      宮崎市
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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