| Project/Area Number |
24591788
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
AOKI Shigeki 順天堂大学, 医学部, 教授 (80222470)
SUZUKI Michimasa 順天堂大学, 医学部, 教授 (20534811)
TANAKA Fumine 順天堂大学, 医学部, 助手 (70621738)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 多発性硬化症 / 視神経脊髄炎 / MRI / 拡散テンソル / DKI / QSI / NODDI / NABT / DTI / q-space imaging(QSI) / optic pathway / q-space imaging (QSI) |
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| Outline of Final Research Achievements |
Normal-appearing brain tissue (NABT) is a factor for movement disorder and higher dysfunction of Multiple sclerosis(MS).
We used Diffusional tensor imaging, DKI and QSI to evaluate NABT of MS.
DTI, DKI, QSI can detect abnormality of NABT, and are helpful for diagnosis, prognosis and therapy evaluation.
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