Multiple sclerosis; Benefits of DTI, DKI, QSI
Project/Area Number |
24591788
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Radiation science
|
Research Institution | Juntendo University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
AOKI Shigeki 順天堂大学, 医学部, 教授 (80222470)
SUZUKI Michimasa 順天堂大学, 医学部, 教授 (20534811)
TANAKA Fumine 順天堂大学, 医学部, 助手 (70621738)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | 多発性硬化症 / 視神経脊髄炎 / MRI / 拡散テンソル / DKI / QSI / NODDI / NABT / DTI / q-space imaging(QSI) / optic pathway / q-space imaging (QSI) |
Outline of Final Research Achievements |
Normal-appearing brain tissue (NABT) is a factor for movement disorder and higher dysfunction of Multiple sclerosis(MS). We used Diffusional tensor imaging, DKI and QSI to evaluate NABT of MS. DTI, DKI, QSI can detect abnormality of NABT, and are helpful for diagnosis, prognosis and therapy evaluation.
|
Report
(4 results)
Research Products
(20 results)
-
[Journal Article] Multiple sclerosis: Benefits of q-space imaging in evaluation of normal-appearing and periplaque white matter2014
Author(s)
Masaaki Hori, Mariko Yoshida, Kazumasa Yokoyama, Koji Kamagata, Fumitaka Kumagai, Issei Fukunaga , Kouhei Kamiya, Michimasa Suzuki, Yoshitaka Masutani, Nozomi Hamasaki ,Yuriko Suzuki, Shinsuke Kyogoku, Nobutaka Hattori, Shigeki Aoki
-
Journal Title
Magn Reson Imaging.
Volume: Mar 18.
Pages: 1,5
DOI
Related Report
Peer Reviewed
-
[Journal Article] Diffusional kurtosis imaging of normal-appearing white matter in multiple sclerosis: preliminary clinical experience.2013
Author(s)
Yoshida M, Hori M, Yokoyama K, Fukunaga I, Suzuki M, Kamagata K, Shimoji K, Nakanishi A, Hattori N, Masutani Y, Aoki S.
-
Journal Title
Jpn J Radiol.
Volume: 31
Pages: 50,55
DOI
Related Report
Peer Reviewed
-
-
[Presentation] neurite orientation and dispersion and density imaging(NODDI)を用いた多発性硬化症のnormal appearing white matterに対する定量解析2014
Author(s)
吉田茉莉子, 堀正明, 横山和正, 鎌形康司, 鈴木通真, 錦織瞭, 濱崎望, 佐藤秀二, 福永一星, 神谷昂平, 京極伸介, 青木茂樹, 服部信孝
Organizer
第42回日本磁気共鳴医学会大会
Place of Presentation
京都
Year and Date
2014-09-18 – 2014-09-20
Related Report
-
[Presentation] Differences in diffusional changes of the optic pathways between Multiple Sclerosis and Neuromyelitis Optica using Diffusional Kurtosis Imaging2014
Author(s)
Mariko Yoshida, Masaaki Hori, Kazumasa Yokoyama, Nozomi Hamasaki, Michimasa Suzuki, Koji Kamagata, Kohei Kamiya, Shigeki Aoki, Yoshitaka Masutani, and Nobutaka Hattori
Organizer
ISMRM 22nd annual meeting
Place of Presentation
Milan, Italy
Year and Date
2014-05-10 – 2014-05-16
Related Report
-
[Presentation] Diffusional Kurtosis Imaging of White Matter and Gray Matter Lesions in Multiple Sclerosis: Combined Use with Double Inversion Recovery2014
Author(s)
Mariko Yoshida, Masaaki Hori, Kazumasa Yokoyama, Nozomi Hamasaki, Michimasa Suzuki, Koji Kamagata, Kohei Kamiya, Shigeki Aoki, Yoshitaka Masutani, and Nobutaka Hattori
Organizer
ISMRM 22nd annual meeting
Place of Presentation
Milan, Italy
Year and Date
2014-05-10 – 2014-05-16
Related Report
-
-
-
[Presentation] Diffusional Kurtosis Imaging of the Optic Pathways between Multiple Sclerosis and Neuromyelitis Optica.2013
Author(s)
Yoshida, M.·Hori, M.・Yokoyama, K.·Suzuki, M.·Kamagata, K.·Kyogoku, S.·Kamiya, K.·Sato, K.·Aoki, S.·Masutani, Y.
Organizer
ASNR, 51st Annual Meeting
Place of Presentation
San Diego, USA.
Year and Date
20130520-20130523
Related Report
-
-
-
[Presentation] Diffusional kurtosis imaging: theory, optimization of protocol, and clinical applications2012
Author(s)
Yoshida, M.・Hori, M.・Fukunaga, I.・Suzuki, M・Kamagata, K. Asahi, K.・Aoki, S.・Masutani, Y.
Organizer
ASNR 50th Annual Meeting & The Foundation of the ASNR Symposium 2012
Place of Presentation
Hilton New York, New York, NY
Year and Date
20120421-20120426
Related Report
-
-
[Presentation] 多発性硬化症患者におけるDiffusional kurtosis imagingを用いた白質の定量的解析2012
Author(s)
吉田茉莉子, 堀正明, 福永一星, 横山和正, 濱崎 望, 鎌形康司, 下地啓五, 中西淳, 鈴木由里子, 桑鶴良平, 笹井啓資, 青木茂樹, 増谷佳孝
Organizer
第72回日本医学放射線学会総会
Place of Presentation
パシフィコ横浜
Year and Date
20120411-20120414
Related Report
-
-
-
-
-
-