| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
Typical single refocused pulsed-gradient spin-echo (SRSE-DWI) sequence is interacted by susceptibility-induced background gradient fields around vessels, while twice-refocused spin-echo (TRSE-DWI) sequence is reduced the effect. The difference between SRSE-DWI and TRSE-DWI will indicate CBV weighted image. We evaluated the ADC reduced ratio in both sequence with computer simulations in a vascular model. We made TRSE-DWI sequence for animal MRI and evaluated on stroke model rats. The simulation results indicate possible criteria for brain stroke validation. The experimental results did not show adequate S/N images. At this moment, we now evaluating the images from normal volunteer and stroke patients.
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