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Development of a new catheter for segmental adrenal venous sampling

Research Project

Project/Area Number 24591808
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionTohoku University

Principal Investigator

Seiji Kazumasa  東北大学, 大学病院, 講師 (50400247)

Co-Investigator(Kenkyū-buntansha) Takase Kei  東北大学, 医学系研究科, 教授 (60361094)
Morimoto Rei  東北大学, 大学病院, 助教 (30547394)
Co-Investigator(Renkei-kenkyūsha) Oota Makoto  東北大学, 流体科学研究所, 准教授 (20400418)
Haga Yoichi  東北大学, 医工学(系)研究科(研究院), 教授 (00282096)
Nakamura Yasuhiro  東北大学, 医学系研究科, 准教授 (80396499)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsインターベンショナルラジオロジー / 血管 / 放射線 / 副腎 / 副腎静脈サンプリング / 原発性アルドステロン症 / カテーテル / 原発性アルドステロン
Outline of Final Research Achievements

Segmental venous sampling is essential for diagnosis and localization of aldosterone producing adenomas. In segmental adrenal venous sampling (S-AVS), blood samples are obtained with microcatheters inserted into the target venous tributary. However, it sometimes happen that blood samples cannot be obtained through catheters. In such cases, it is assumed that suction pressure deforms venous wall, then catheter tip is considered to be occluded. To our knowledge, there has been no study concerning hemodynamics in venous catheter blood sampling. The purpose of this study is to simulate the blood flow in venous blood sampling using synthetic very small blood vessel or Computational Fluid Dynamics method and to search the catheter tip shape suitable for the procedure.
The prototype of microcatheter whose tip was shaped suitable for S-AVS was created. And then, the performance of the microcatheter was evaluated in an animal study.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (5 results)

All 2016 2015 2014 2013

All Presentation (5 results)

  • [Presentation] Development of a new catheter for selective venous sampling: a new study with improved model2016

    • Author(s)
      木下 知、清治和将、太田 信、高瀬 圭
    • Organizer
      ECR 2016
    • Place of Presentation
      ウィーン(オーストリア)
    • Year and Date
      2016-03-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] Development of a New Catheter with Innovative Concepts for Selective Ven ous Sampling- Preliminary CFD Study2015

    • Author(s)
      木下 知、清治和将、高瀬 圭、太田 信
    • Organizer
      12th ICFD(International Conference on Flow Dynamics)
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2015-10-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] Development of a new catheter for selective venous sampling: a primary C FD study2015

    • Author(s)
      木下 知、清治和将、高瀬 圭、松本 翔、太田 信
    • Organizer
      ECR(European congress of radiology)2015
    • Place of Presentation
      オーストリア、ウィーン
    • Year and Date
      2015-03-04 – 2015-03-08
    • Related Report
      2014 Research-status Report
  • [Presentation] Development of a new catheter for selective venous sampling2014

    • Author(s)
      木下 知、清治和将、高瀬 圭、松本 翔、太田 信
    • Organizer
      COMSOL Conference Tokyo 2014
    • Place of Presentation
      東京 秋葉原
    • Year and Date
      2014-12-05
    • Related Report
      2014 Research-status Report
  • [Presentation] Development of a new catheter with innovative concept for selective venous sampling - preliminary study2013

    • Author(s)
      木下 知、清治和将、大竹 匡、太田 信、権 貴龍
    • Organizer
      10th ICFD (International Conference of Flow Dynamics)
    • Place of Presentation
      仙台国際センター
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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