| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
This study was prformed at Spring-8, Hyogo Japan, using synchrotron radiation.
Normal tissue tolerance to ultra-high dose rate radiation was examined using C57/BL6 mice brain in vivo. The comparison between broad beam and several slit beams irradiation revealed that a LD50 of slitbeam (500 Gy)achieved approximately 7-folds higher than that of broad beam(70 Gy). Moreover, the slit beam irradiation did not cause severe neuronalcells loss. The slit beam irradiation to the brain did not induce abnormal behavior disorder in mice. The slit beam irradiation to the spinal cord did not cause any difference to that of broad beam irradiation.
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