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Simulation of chronological changes of the stent graft after implantation in the abdominal aortic aneurysm

Research Project

Project/Area Number 24591866
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field General surgery
Research InstitutionThe University of Tokyo

Principal Investigator

OKAMOTO Hiroyuki  東京大学, 医学部附属病院, 登録研究医 (60348266)

Co-Investigator(Kenkyū-buntansha) MIYATA Tetsurou  東京大学, 医学部附属病院, 届出研究医 (70190791)
SHIGEMATSU Kunihiro  東京大学, 医学部附属病院, 講師 (20215966)
HOSHINA Katsuyuki  東京大学, 医学部附属病院, 講師 (90571761)
OHSHIMA Mari  東京大学, その他の研究科, 教授 (40242127)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywordssimulation / modeling system / stent graft / migration / aortic aneurysm / curvature / torsion / 大動脈 / ステントグラフト / シミュレーション / 瘤 / 腹部大動脈瘤 / 構造解析
Outline of Final Research Achievements

Stent graft changes chronologically after implantation into the abdominal aortic aneurysm, and the behaviors differed among devices. We revealed that mechanical factors such as curvature (angulation) or torsion changes gradually after the implantation and numerically expressed and visualized, with our own modeling system. We are able to reveal the risk of migration case-specifically, which is considered to be helpful clinically.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (13 results)

All 2015 2014 2013 2012

All Journal Article (7 results) (of which Peer Reviewed: 7 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (6 results)

  • [Journal Article] Development of an Image-Based Modeling System to Investigate Evolutional Geometric Changes of a Stent Graft in an Abdominal Aortic Aneurysm2015

    • Author(s)
      Masaharu Kobayashi, Katsuyuki Hoshina, Sota Yamamoto, Youkou Nemoto, Takafumi Akai, Kunihiro Shigematsu, Toshiaki Watanabe, Marie Ohshima
    • Journal Title

      Circulation Journal

      Volume: 79 Issue: 7 Pages: 1534-1541

    • DOI

      10.1253/circj.CJ-15-0037

    • NAID

      130005083933

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Outcomes and Morphologic Changes After Endovascular Repair for Abdominal Aortic Aneurysms With a Severely Angulated Neck2013

    • Author(s)
      Hoshina K, Okamoto H, Shigematsu K, Miyata T, et al.
    • Journal Title

      Circulation Journal

      Volume: 77 Issue: 8 Pages: 1996-2002

    • DOI

      10.1253/circj.CJ-13-0204

    • NAID

      10031178667

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Aortic dissectin occurring 18 months after successful endovascular repair in an anatomical difficult case of abdominal aortic aneurysm.2013

    • Author(s)
      Yamamoto S, Hoshina K, Takazawa Y, Okamoto H, Shigematsu K, Miyata T, Watanabe T.
    • Journal Title

      Case Report Vasc Med

      Volume: 412708 Pages: 412708-412708

    • DOI

      10.1155/2013/412708

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Study Design of PROCEDURE Study a Randomized Comparison of the Dose-Dependent Effects of Pitavastatin in Patients with Abdominal Aortic Aneurysm with Massive Aortic Atheroma: Prevention of Cholesterol Embolization during Endovascular and Open Aneurysm Repair with Pitavastatin(PROCEDURE) Study2013

    • Author(s)
      Hoshina K, Nemoto M, Hashimoto T, Miura S, Urabe G, Nakazawa T, Hosaka A, Kato M, Ohkubo N, Miyairi T, Okamoto H, Shigematsu K, Miyata T
    • Journal Title

      Annals of Vascular Diseases

      Volume: 6 Issue: 1 Pages: 62-66

    • DOI

      10.3400/avd.oa.12.00064

    • NAID

      130004487985

    • ISSN
      1881-641X, 1881-6428
    • Related Report
      2013 Research-status Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Statins Reduce Extensive Aortic Atheromas in Patients with Abdominal Aortic Aneurysms2013

    • Author(s)
      Nemoto M, Hoshina K, Takayama T, Miura S, Nakazawa T, Kato M, Shigematsu K, Miyata T, Watanabe T.
    • Journal Title

      Annals of Vascular Diseases

      Volume: 6 Issue: 4 Pages: 711-717

    • DOI

      10.3400/avd.oa.13-00065

    • NAID

      130004488026

    • ISSN
      1881-641X, 1881-6428
    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Lessons learned from a case of abdominal aortic aneurysm accompanied by unstable coagulopathy.2012

    • Author(s)
      Hoshina K, Kaneko M, Hosaka A, Okamoto H, Shigematsu K, Miyata T.
    • Journal Title

      Case Report in Vascular Medicine

      Volume: 265860 Pages: 1-5

    • DOI

      10.1155/2012/265860

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Acute Remodeling of an Adjoining Aneurysm after Endovascular Treatment of a Ruptured Splanchnic Arterial Aneurysm: A Case of Clinically Diagnosed Segmental Arterial Mediolysis2012

    • Author(s)
      Nishikawa Y, Hoshina K, Sasaki H, Hosaka A, Yamamoto K, Okamoto H, Shigematsu K, Miyata T.
    • Journal Title

      Annals of Vascular Diseases

      Volume: 5 Issue: 4 Pages: 449-453

    • DOI

      10.3400/avd.cr.12.00060

    • NAID

      130004713555

    • ISSN
      1881-641X, 1881-6428
    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 大動脈のシミュレーション研究における医工連携とその成果2014

    • Author(s)
      保科克行、赤井隆文、根元洋光、大島まり、山本創太、山内治雄、小野稔、重松邦広、渡邉聡明
    • Organizer
      日本脈菅学会総会
    • Place of Presentation
      倉敷
    • Year and Date
      2014-10-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 大動脈瘤の二次元構造解析による嚢状瘤の定義2014

    • Author(s)
      保科克行 、赤井隆文、竹内浩明、山本創太、大島まり、根元洋光、西山綾子、宮原拓也、保坂晃弘、岡本宏之、重松邦広、宮田哲郎、渡邊聡明
    • Organizer
      第114回日本外科学会定期学術集会
    • Place of Presentation
      京都(国立京都国際会館)
    • Related Report
      2013 Research-status Report
  • [Presentation] ステントグラフト留置後の形態変化の評価:モデリングシステムの開発2014

    • Author(s)
      保科克行、小林匡治、大島まり、山本創太、赤井隆文、根元洋光、保坂晃弘、宮原拓也、岡本宏之、重松邦広、宮田哲郎、渡邉聡明
    • Organizer
      第44回日本心臓血管外科学会総会
    • Place of Presentation
      熊本(ホテル日航熊本)
    • Related Report
      2013 Research-status Report
  • [Presentation] 大動脈ステントグラフトのbranch protection:最善の手法とは?2013

    • Author(s)
      保科克行、加藤雅明、根本卓、須原正光、白須拓郎、芳賀真、望月康晃、根元洋光、松倉満、赤井隆文、谷口良輔、山本諭、西山綾子、保坂晃弘、宮原拓也、岡本宏之、重松邦広、宮田哲郎、渡邉聡明
    • Organizer
      第54回日本脈管学会総会
    • Place of Presentation
      東京(ステーションコンファレンス東京)
    • Related Report
      2013 Research-status Report
  • [Presentation] Type 2 Endoleakに対するコイル塞栓術3例と今後の治療戦略について2013

    • Author(s)
      保科克行、赤羽正章、保坂晃弘、加藤雅明、宮原拓也、岡本宏之、重松邦広、大久保修和、宮田哲郎
    • Organizer
      第17回大動脈ステントグラフト研究会
    • Place of Presentation
      青森(ホテル青森)
    • Related Report
      2013 Research-status Report
  • [Presentation] 瘤頸部高度屈曲症例に対するステントグラフト内挿術後の経時的変化と合併症:デバイスごとの検討とシミュレーションの役割2012

    • Author(s)
      保科克行、赤井隆文、加藤雅明、浦部豪、中澤達、大島まり、山本創太、白須拓郎、芳賀真、望月康晃、松倉満、谷口良輔、根本卓、山本諭、赤井淳、西山綾子、保坂晃弘、岡本宏之、重松邦広、宮田哲郎
    • Organizer
      第53回日本脈管学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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