Translational research for deceased donor liver transplantation
Project/Area Number |
24591882
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
General surgery
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Research Institution | Ehime University |
Principal Investigator |
TAKADA Yasutsugu 愛媛大学, 医学(系)研究科(研究院), 教授 (10272197)
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Project Period (FY) |
2012-04-01 – 2015-03-31
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Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Keywords | 肝移植 / 心停止ドナー / トランスレーショナル・リサーチ |
Outline of Final Research Achievements |
Use of liver grafts from donors after cardiac death (DCD) is one of the ways to attenuate the organ shortage in clinical liver transplantation (LT). To introduce the DCD-LT in Japan, we conducted a study of porcine LT using DCD as a translational research. As a results, porcine model of DCD-LT operation has been established. In addition, the efficacy of pharmacological graft protection has been suggested.
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Report
(4 results)
Research Products
(24 results)
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[Journal Article] Randomized, multicenter trial comparing tacrolimus plus mycophenolate mofetil to tacrolimus plus steroid in hepatitis C virus-positive recipients of living donor liver transplantation.2013
Author(s)
Takada Y, Kaido T, Asonuma K, Sakurai H, Kubo S, Kiuchi T, Inomata Y, Isaji S, Tsumura H, Teramukai S, Matsubara Y, Sakabayashi S, Uemoto S.
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Journal Title
Liver Transplantation
Volume: 19
Pages: 896-906
Related Report
Peer Reviewed
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[Presentation] The clinical course of preoperative anti-HLA antibody-positive rwcipients after liver transplantation.2014
Author(s)
Tohyama T, Watanabe J, Hatano M, Ito E, Inoue H, Kageyama S, Takai A, Mizumoto T, Kushihata F, Takada Y
Organizer
The 2014 Joint International Congress of ILTS, ELITA & LICAGE
Place of Presentation
London, UK
Year and Date
2014-06-04 – 2014-06-07
Related Report
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[Presentation] Long-term course of five patients who underwent liver transplantation with small-for-size grafts with a hemi-portocaval shunt.2014
Author(s)
Ito E, Tohyama T, Watanabe J, Hatano M, Inoue H, Kageyama S, Mizumoto T, Takai A, Kushihata F, Takada Y
Organizer
The 2014 Joint International Congress of ILTS, ELITA & LICAGE
Place of Presentation
London, UK
Year and Date
2014-06-04 – 2014-06-07
Related Report
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[Presentation] Randomized Trial Comparing Tacrolimus And Steroid With Tacrolimus And Mycophenolate Mofetil Among HCV Positive Recipients In Living Donor Liver Transplantation.2012
Author(s)
Yasutsugu Takada, Toshimi Kaido, Katsuhiro Asonuma, Hiroyuki Sakurai, Shoji Kubo, Tetsuya Kiuchi, Yukihiro Inomata, Shuji Isaji, Shinji Uemoto.
Organizer
The 2012 (18th) Joint international congress of ILTS(International Liver Transplantation Society), ELITA, LICAGE
Place of Presentation
San Francisco, USA
Related Report
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