Application and development of endoscopic treatment technology by pulsed water jet
| Project/Area Number |
24591931
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
NAKANO Toru 東北大学, 大学病院, 助教 (50451571)
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| Co-Investigator(Kenkyū-buntansha) |
KAMEI Takashi 東北大学, 医学系研究科, 准教授 (10436115)
NAKAGAWA Atsuhiro 東北大学, 大学病院, 特任助教 (10447162)
NAKAI Masaaki 東北大学, 金属材料研究所, 准教授 (20431603)
MIYATA Go 東北大学, 医学系研究科, 非常勤講師 (60282076)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 食道 / 粘膜下層剥離 / 粘膜下層剥離術 |
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| Outline of Final Research Achievements |
In recent years, endoscopic submucosal dissection (ESD) in the digestive tract has been rapidly spread. Thermal damage can not be avoided by using the electric knife, thus, bleeding is likely to lead to serious complications such as perforation. In this study, we developed the prototype of the pulsed water jet scalpel for ESD and investigated the optimal parameter of the pulsed jet and instrument included suitable material for laser oscillation part in engineering. In animal experiments under general anesthesia, ESD was performed and showed its efficacy and safety。The mechanism of the selective dissection was analyzed by measuring the physical properties of each layer of the esophagus.
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Report
(4 results)
Research Products
(19 results)
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[Journal Article] The Dissection Profile And Mechanism of Tissue-Selective Dissection of The Piezo Actuator Driven Pulsed Water Jet As A Surgical Instrument: Laboratory Investigation Using Swine Liver2014
Author(s)
Yamada M, Nakano T, Sato C, Atsuhiro N, Fujishima F, Kawagishi N, Nakanishi C, Sakurai T, Miyata G, Tomonaga T, Ohuchi N
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Journal Title
Eur Surg Res
Volume: 53
Pages: 61-72
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Experimental application of pulsed laser-induced water jet for endoscopic submucosal dissection: mechanical investigation and preliminary experiment in swine2013
Author(s)
Sato C, Nakano T, Nakagawa A, Yamada M, Yamamoto H, Kamei T, Miyata G, Sato A, Fujishima F, Nakai M, Niinomi M, Takayama K, Tominaga T, Satomi S.
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Journal Title
Dig Endosc
Volume: 25
Pages: 255-263
Related Report
Peer Reviewed
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[Journal Article] Esophagectomy using a thoracoscopic approach with an open laparotomic or hand-assisted laparoscopic abdominal stage for esophageal cancer: analysis of survival and prognostic factors in 315 patients2013
Author(s)
11. Ichikawa H, Miyata G, Miyazaki S, Onodera K, Kamei T, Hoshida T, Kikuchi H, Kanba R, Nakano T, Akaishi T, Satomi S
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Journal Title
Ann Surg
Volume: 257
Pages: 873-875
Related Report
Peer Reviewed
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[Presentation] Effects of low-carbohydrate enteral nutrition on the stabilization of blood sugar level after esophageal surgery: a randomized controlled trial2013
Author(s)
Nakno T, Miyata G, Naoshima K, Kamei T, Abe S, Katsura K, TaniyamaY, Mitamura A, Teshima J, Ohuchi N
Organizer
10th European Sciety of Parenteral and Enteral Neutrition
Place of Presentation
Leipzig, Germany
Related Report
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