Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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Outline of Final Research Achievements |
We used indocyanine green (ICG) fluorescence angiography to quantitatively assess free jejunal graft (FJG) blood perfusion in archived fluorescence video files from FJG transfer patients. We measured the maximum fluorescence intensity at the FJG and the duration (T1/2max) between when the intensity began rising and when it reached half of the maximum. Retrospective assessment showed that the mean T1/2max at the FJG serosae was significantly longer in venous anastomotic failure patients than that in FJGs with good blood perfusion. In postoperative assessment using monitoring flap, which prepared by a part of FJG intraoperatively, the T1/2max of venous failure patients was significantly delayed, too. Our analysis revealed that a T1/2max >9.6 s in intraoperative assessment, and a T1/2max >6.8 in postoperative assessment may be a good indicator of FJG venous malperfusion. Quantitative analysis of ICG fluorescence angiography proved useful for detecting venous anastomotic failure of FJG.
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