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Quantitative assessment of the intestinal tract perfusion using the ICG fluorescence angiography

Research Project

Project/Area Number 24591938
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Digestive surgery
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

KINJI Kamiya  浜松医科大学, 医学部附属病院, 講師 (20324361)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords食道癌 / 下咽頭・頚部食道癌 / 遊離空腸再建 / ICG血管造影
Outline of Final Research Achievements

We used indocyanine green (ICG) fluorescence angiography to quantitatively assess free jejunal graft (FJG) blood perfusion in archived fluorescence video files from FJG transfer patients. We measured the maximum fluorescence intensity at the FJG and the duration (T1/2max) between when the intensity began rising and when it reached half of the maximum. Retrospective assessment showed that the mean T1/2max at the FJG serosae was significantly longer in venous anastomotic failure patients than that in FJGs with good blood perfusion. In postoperative assessment using monitoring flap, which prepared by a part of FJG intraoperatively, the T1/2max of venous failure patients was significantly delayed, too. Our analysis revealed that a T1/2max >9.6 s in intraoperative assessment, and a T1/2max >6.8 in postoperative assessment may be a good indicator of FJG venous malperfusion. Quantitative analysis of ICG fluorescence angiography proved useful for detecting venous anastomotic failure of FJG.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (9 results)

All 2015 2014 2012 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (8 results)

  • [Journal Article] Quantitative assessment of the free jejunal graft perfusion.2015

    • Author(s)
      Kamiya K, Unno N, Miyazaki S, Sano M, Kikuchi H, Hiramatsu Y, Ohta M, Yamatodani T, Mineta H, Konno H
    • Journal Title

      J Surg Res

      Volume: 194 Issue: 2 Pages: 394-399

    • DOI

      10.1016/j.jss.2014.10.049

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 食道癌手術におけるICG血管造影法を用いた術中胃管血流評価の有用性2014

    • Author(s)
      神谷欣志、平松良浩、菊池寛利、宮﨑真一郎、尾﨑裕介、川端俊貴、松本知拓、太田 学、坂口孝宜、海野直樹、今野弘之、大和谷 崇
    • Organizer
      第69回日本消化器外科学会総会
    • Place of Presentation
      郡山市
    • Year and Date
      2014-07-16 – 2014-07-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] ICG血管造影による下咽頭・頚部食道癌切除後再建グラフトの新しい術中血流評価法2012

    • Author(s)
      神谷欣志
    • Organizer
      第37回日本外科系連合学会学術集会
    • Place of Presentation
      福岡市
    • Related Report
      2012 Research-status Report
  • [Presentation] ICG血管造影を用いた遊離空腸術中血流評価法2012

    • Author(s)
      神谷欣志
    • Organizer
      第67回日本消化器外科学会総会
    • Place of Presentation
      富山市
    • Related Report
      2012 Research-status Report
  • [Presentation] ICG蛍光血管造影による遊離空腸術後血流評価

    • Author(s)
      神谷欣志
    • Organizer
      第113回日本外科学会定期学術集会
    • Place of Presentation
      福岡
    • Related Report
      2013 Research-status Report
  • [Presentation] ICG蛍光血管造影による遊離空腸の周術期血流評価

    • Author(s)
      神谷欣志
    • Organizer
      第68回日本消化器外科学会総会
    • Place of Presentation
      宮崎
    • Related Report
      2013 Research-status Report
  • [Presentation] 嚥下造影動画解析による胸部食道癌術後嚥下機能評価

    • Author(s)
      神谷欣志
    • Organizer
      JDDW2013
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report
  • [Presentation] 遊離空腸再建における周術期血流評価へのICG蛍光血管造影法の応用

    • Author(s)
      神谷欣志
    • Organizer
      第6回蛍光Navigation Surgery 研究会
    • Place of Presentation
      神戸
    • Related Report
      2013 Research-status Report
  • [Presentation] 下咽頭・頚部食道癌切除後の移植腸管における周術期血流評価-ICG血管造影法による客観的評価法の確立を目指して-

    • Author(s)
      神谷欣志
    • Organizer
      第50回日本腹部救急医学会総会
    • Place of Presentation
      東京
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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