| Project/Area Number |
24592044
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Thoracic surgery
|
|---|
| Research Institution | Hirosaki University |
|---|
Principal Investigator |
FUKUDA Wakako 弘前大学, 医学(系)研究科(研究院), 助教 (90598715)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
FUKUDA Ikuo 弘前大学, 医学(系)研究科(研究院), 教授 (50344594)
DAITOKU Kazuyuki 弘前大学, 医学部附属病院, 准教授 (50374822)
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
|---|
| Keywords | 外科 / 流体工学 / コンピューター・シミュレーション / 体外循環 / 大腿動脈送血 / 脳塞栓 / 動脈硬化症 / 送血法 / 大動脈粥状硬化 / 胸部大動脈瘤 / 末梢動脈送血 / 血流シミュレーション / 三次元血流解析 / アテローム塞栓症 / 脳合併症 |
|---|
| Outline of Final Research Achievements |
Extracorporeal circulation is an important adjunctive technique for cardiovascular surgery. In cardiopulmonary bypass, blood with low oxygen content is withdrawn from large veins, introducing artificial lung to exchange oxygen and bicarbonate. Oxygenated blood is introduced directly into the aorta or through peripheral arteries. Arterial perfusion from the femoral artery is one of the easiest procedure because of easiness of exposure and enough diameter. This method is convenient for reoperation or minimally invasive cardiac surgery. However, atheroembolism due to retrograde perfusion from the femoral artery is emerging problem in elderly patients. We studied flow velocity and shear stress in the aorta and its branches using computed simulation technique. We compared two method for femoral artery perfusion: direct cannulation vs. side-armed graft method. Flow velocity and shear stress was lower in the side-army graft method than that in direct cannulation.
|
