Observation of Aneurysm growth using 3D registration technique
| Project/Area Number |
24592114
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KIN Taichi 東京大学, 医学部附属病院, 助教 (90447392)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 脳動脈瘤 / 三次元画像 / 画像検査 / 増大 / セグメンテーション / 閾値 / レジストレーション / コンピューターシミュレーション / 血行力学的ストレス |
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| Outline of Final Research Achievements |
Unruptured cerebral aneurysms should be observed meticulously as to the changes in size and shape. However, detecting sub-millimeter change is not easy since it is difficult to observe the lesion from the same viewpoint. In this research, we determined the optimal threshold for segmentation to be 0.5 x (maximum intensity + background intensity). We introduced cross-correlation method to register the 3D datasets of a certain patient obtained at different timings. The precisions of registrations were less than 1 mm for skulls and around 1 mm for cerebral arteries. We found that cerebral aneurysms tend to grow not eccentric but uniform way.
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Report
(4 results)
Research Products
(18 results)
