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Observation of Aneurysm growth using 3D registration technique

Research Project

Project/Area Number 24592114
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cerebral neurosurgery
Research InstitutionThe University of Tokyo

Principal Investigator

SHOJIMA Masaaki  東京大学, 医学部附属病院, 助教 (80376425)

Co-Investigator(Kenkyū-buntansha) KIN Taichi  東京大学, 医学部附属病院, 助教 (90447392)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords脳動脈瘤 / 三次元画像 / 画像検査 / 増大 / セグメンテーション / 閾値 / レジストレーション / コンピューターシミュレーション / 血行力学的ストレス
Outline of Final Research Achievements

Unruptured cerebral aneurysms should be observed meticulously as to the changes in size and shape. However, detecting sub-millimeter change is not easy since it is difficult to observe the lesion from the same viewpoint. In this research, we determined the optimal threshold for segmentation to be 0.5 x (maximum intensity + background intensity). We introduced cross-correlation method to register the 3D datasets of a certain patient obtained at different timings. The precisions of registrations were less than 1 mm for skulls and around 1 mm for cerebral arteries. We found that cerebral aneurysms tend to grow not eccentric but uniform way.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (18 results)

All 2015 2014 2013 2012 Other

All Journal Article (9 results) (of which Peer Reviewed: 7 results,  Acknowledgement Compliant: 1 results) Presentation (9 results) (of which Invited: 4 results)

  • [Journal Article] Computational Fluid Dynamic Simulation of a Giant Basilar Tip Aneurysm with Eventual Ruputre After Hunterian Ligation2014

    • Author(s)
      Masaaki Shojima, Akio Morita, Toshikazu Kimura, Marie Oshima, Taich Kin, Nobuhito Saito
    • Journal Title

      World Neurosurgery

      Volume: 82 Issue: 3-4 Pages: 5-9

    • DOI

      10.1016/j.wneu.2013.09.034

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Translation of computational fluid dynamics study to neurosurgery2014

    • Author(s)
      Shojima M, Saito N.
    • Journal Title

      World Neurosurgery

      Volume: 83 Issue: 1 Pages: 15

    • DOI

      10.1016/j.wneu.2013.07.085

    • URL

      https://pure.teikyo.jp/en/publications/a7b6e250-202e-4156-a2ea-03717ccf3b4e

    • Related Report
      2013 Research-status Report
  • [Journal Article] Surgical simulation of cerebrovascular disease with multimodal fusion 3-dimensional computer graphics2014

    • Author(s)
      Saito N, Kin T, Oyama H, Yoshino M, Nakagawa D, Shojima M, Imai H, Nakatomi H.
    • Journal Title

      Neurosurgery

      Volume: 60 Issue: SUPPL. 1 Pages: 24

    • DOI

      10.1227/01.neu.0000430312.71326.6d

    • URL

      https://pure.teikyo.jp/en/publications/e0762506-1441-458f-9b6b-74861adf5337

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 脳動脈瘤の流体解析で何がわかるか2013

    • Author(s)
      庄島正明
    • Journal Title

      Clinical Neuroscience

      Volume: 31 Pages: 417-420

    • Related Report
      2012 Research-status Report
  • [Journal Article] A high-resolution method with increased matrix size can characterize small arteries around a giant aneurysm in three dimensions2012

    • Author(s)
      Yoshino M, Kin T, Shojima M, Nakatomi H, Oyama H, Saito N.
    • Journal Title

      Br J Neurosurg

      Volume: 26 Issue: 6 Pages: 927

    • DOI

      10.3109/02688697.2012.692840

    • URL

      https://localhost/en/publications/8e021ea2-f3f7-4ad5-8964-96e5bfd75568

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] A new strategic neurosurgical planning tool for brainstem cavernous malformations using interactive computer graphics with multimodal fusion images.2012

    • Author(s)
      Kin T, Nakatomi H, Shojima M, Tanaka M, Ino K, Mori H, Kunimatsu A, Oyama H, Saito N.
    • Journal Title

      J Neurosurg.

      Volume: 117(1) Issue: 1 Pages: 78-88

    • DOI

      10.3171/2012.3.jns111541

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Double independent spinal dural arteriovenous fistulas at the thoracic spine2012

    • Author(s)
      Hanakita S, Takai K, Kin T, Shojima M, Saito N.
    • Journal Title

      Acta Neurochir (Wien)

      Volume: 154 Issue: 7 Pages: 1157

    • DOI

      10.1007/s00701-012-1366-5

    • URL

      https://localhost/en/publications/0d41fe95-8a77-467b-a832-fb3edd433092

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Role of Gamma Knife surgery in the treatment of intracranial dural arteriovenous fistulas.2012

    • Author(s)
      Hanakita S, Koga T, Shin M, Shojima M, Igaki H, Saito N.
    • Journal Title

      J Neurosurg

      Volume: 117 Suppl Issue: Special_Suppl Pages: 158

    • DOI

      10.3171/2012.7.gks12967

    • URL

      https://pure.teikyo.jp/en/publications/72936b83-8826-4782-bad8-ca26241fc566

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Role of stereotactic radiosurgery in the treatment of high-grade cerebral arteriovenous malformation.2012

    • Author(s)
      Hanakita S, Koga T, Shin M, Shojima M, Igaki H, Saito N
    • Journal Title

      Neurol Med Chir (Tokyo)

      Volume: 52 Pages: 845-851

    • NAID

      10031131525

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] コンピューターシミュレーションによる血流解析の結果をいかに解釈するか2015

    • Author(s)
      庄島正明
    • Organizer
      Asahikawa Neurosurgery Winter Seminar
    • Place of Presentation
      北海道旭川市
    • Year and Date
      2015-02-24
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 脳血管疾患における血流動態:直接計測とシミュレーションの役割2014

    • Author(s)
      庄島正明
    • Organizer
      Software Cradle User Conference 2014
    • Place of Presentation
      東京都渋谷区
    • Year and Date
      2014-10-17
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 脳血管病変における血流評価の意義と臨床での展開2014

    • Author(s)
      庄島正明
    • Organizer
      Parallel Imaging Symposium in Hokkaido
    • Place of Presentation
      北海道札幌市
    • Year and Date
      2014-08-02
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 血液のレオロジーと脳血管病変2014

    • Author(s)
      庄島正明
    • Organizer
      第1回心血管脳卒中学会
    • Place of Presentation
      埼玉県さいたま市
    • Year and Date
      2014-05-29
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 脳スクリーニング検査における脳動脈瘤とプラーク潰瘍の鑑別2012

    • Author(s)
      庄島正明 伊藤明博 鈴木康隆 金太一 吉野正紀 斉藤延人
    • Organizer
      第37回日本脳卒中学会総会
    • Place of Presentation
      福岡
    • Related Report
      2012 Research-status Report
  • [Presentation] 三次元画像に基づく硬膜動静脈瘻の治療戦略2012

    • Author(s)
      庄島 正明 伊藤明博 鈴木康隆 吉野正紀 金太一 中冨浩文 斉藤延人
    • Organizer
      第71回日本脳神経外科学会総会
    • Place of Presentation
      大阪
    • Related Report
      2012 Research-status Report
  • [Presentation] 三次元画像に基づく硬膜動静脈瘻の治療(シンポジウム)2012

    • Author(s)
      庄島 正明 伊藤明博 鈴木康隆 吉野正紀 金太一 中冨浩文 斉藤延人
    • Organizer
      第28回日本脳神経血管内治療学会総会
    • Place of Presentation
      仙台
    • Related Report
      2012 Research-status Report
  • [Presentation] Water hammer effectと脳神経外科疾患

    • Author(s)
      庄島正明
    • Organizer
      第61回 レオロジー討論会
    • Place of Presentation
      仙台
    • Related Report
      2013 Research-status Report
  • [Presentation] 血流変向による脳動脈瘤治療 -血流シミュレーションによる研究

    • Author(s)
      庄島正明
    • Organizer
      第42回日本脳卒中の外科学会
    • Place of Presentation
      品川
    • Related Report
      2013 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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