Neuromodulation for neuronal recovery

• Project/Area Number: 24592137
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cerebral neurosurgery
• Research Institution: Oita University
• Principal Investigator: FUJIKI Minoru 大分大学, 医学部, 教授 (90231563)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
• Keywords: 脳虚血 / 神経細胞死 / 虚血耐性 / 磁気刺激 / 遺伝子発現 / BDNF / 神経保護 / 神経修復 / ＢＤＮＦ

Outline of Final Research Achievements

We estimated BDNF expression for neuronal recovery after stroke or spinal cord injury. Activity dependent BDNF upregulation, non-invasively without neuronal injury, is essential for neuronal functional recovery according with neuronal plasticity. Future device development with technological department is necessary.