Establishment of a rodent model of functional neuromuscular stimulation for motor therapy after spinal cord injury
| Project/Area Number |
24592199
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 脊髄損傷 / リハビリテーション / 機能的電気刺激 |
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| Outline of Final Research Achievements |
We examined the effectiveness of functional electrical stimulation with kHz in gait rhythm stimulation therapy. Tests were performed using 20 mature female Fischer rats.FNS was administered for three days from seventh day post-injury. Rats were divided into four groups (5 rats/group), including the FNS treatment 75 Hz group (iSCI FNS 75Hz), 8 kHz group (iSCI FNS 8 kHz), injury control group (iSCI-NT), and normal group (Normal-CT), and compared. There was no significant difference in BBB scores at any point between the four groups. In 3D gait analysis, compared with the injury control group, the 8 kHz group showed a significant improvement in synergistic movement of both hindlimb. We suggest that kHz stimulation is effective in gait rhythm stimulation using NMES.
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Report
(4 results)
Research Products
(11 results)
