| Project/Area Number |
24592201
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kochi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KIDA Kazunobu 高知大学, 教育研究部医療学系, 講師 (30325419)
ISHIDA Kenji 高知大学, その他, 教授相当 (10274367)
IKEUCHI Masahiko 高知大学, 教育研究部医療学系, 教授 (00372730)
KUMON Masashi 高知大学, 教育研究部医療学系, 助教 (20380371)
IZUMI Masashi 高知大学, 医学部附属病院, その他 (60420569)
TADOKORO Nobuaki 高知大学, 医学部附属病院, その他 (20457401)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 腰部脊柱管狭窄症 / 間欠跛行 / 保存療法 / 脛骨神経 / 反復電気刺激 / F波 / ニューロモデュレーション / 末梢神経刺激 |
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| Outline of Final Research Achievements |
We studied the effects of repetitive tibial nerve stimulation (RTNS) on neurogenic claudication and F-wave conduction in a total of 45 patients with central lumbar spinal stenosis (LSS) as compared with 13 age- and sex-matched healthy volunteers. A conditioning RTNS consisted of 0.3 ms in duration and of an intensity 20% higher than the motor threshold, applied at a rate of 5/s for 5 minutes to the ankle.
RTNS significantly increased claudication distance and the F-wave conduction velocity in the LSS group, but not in the control group. In the LSS group, this effect of RTNS on the F-wave was demonstrated not only on the side ipsilateral to RUNS but also on the contralateral side.
Evidenced by this study, RTNS should have practical value in providing a new therapeutic modality for LSS. The technique can be carried out at home with a portable stimulator running on lithium batteries for LSS patients to reduce claudication symptoms.
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