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Elucidation of the mechanism of myelination by glucocorticoids.

Research Project

Project/Area Number 24592208
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

FUJIWARA HIROYOSHI  京都府立医科大学, 医学(系)研究科(研究院), 准教授 (90381962)

Co-Investigator(Kenkyū-buntansha) ODA RYO  京都府立医科大学, 医学研究科, 講師 (80516469)
TOKUNAGA DAISAKU  京都府立医科大学, 医学研究科, 准教授 (90343409)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords末梢神経 / グルココルチコイド / 神経再生
Outline of Final Research Achievements

Glucocorticoids improve the symptoms of peripheral nerve disorders, such as carpal tunnel syndrome and peripheral neuropathy.Schwann cells of the peripheral nerves express glucocorticoid receptors (GR), and glucocorticoids enhance the rate of myelin formation in vitro. Moreover, label-free biochemical imaging with Raman spectroscopy can be used to detect turnover of axon and myelin in peripheral nerve regeneration.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (1 results)

All 2015

All Presentation (1 results)

  • [Presentation] 直流電気刺激による末梢神経再生因子の解析2015

    • Author(s)
      市丸宏三、藤原浩芳、森崎真介、小田 良、久保俊一
    • Organizer
      第42回生体電気・物理刺激研究会
    • Place of Presentation
      東京都港区
    • Year and Date
      2015-03-14
    • Related Report
      2014 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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