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Devlopment of artificial joints using carbon nanotube added titanium alloy

Research Project

Project/Area Number 24592221
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionChiba University

Principal Investigator

SUZUKI MASAHIKO  千葉大学, フロンティア医工学センター, 教授 (10312951)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsカーボンナノチューブ / 人工関節 / チタン合金 / 摩耗 / UHMWPE / 骨芽様細胞 / Metal on metal
Outline of Final Research Achievements

The pin on disc tests (400000 cycles) were carried out using Til6Al4V, CoCrMo, and 0.9%wt CNT (carbon nanotube) added Ti6Al4V discs and UHMWPE (ultra-high molecular polyethylene, GIR1050) pins. The wear volumes in three groups were 3.8 mm3, 3.8 mm3 and 3.0 mm3, respectively. The wear volume of Ti6Al4V disc and GUR1050 pin was similar to that of CoCrMo disc. The wear volume of 0.9%wt CNT added Ti6Al4V disc was reduced by approximately 25 percent. The cell growth rates with mouse osteoblast-like cells were similar between on Ti6Al4V discs and on 0.9%wt CNT added Ti6Al4V discs. To gain further wear resistance, the diamond-like carbon process and the carbon-doped titanium oxide process were performed toTi6Al4V discs, respectively. The diamond-like carbon membrane on Ti6Al4V discs were peeled off during the pin on disc tests. The wear volume of carbon-doped titanium oxide treated Ti6Al4V disc was reduced by approximately 50 percent.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (4 results)

All 2013 2012

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results)

  • [Journal Article] カーボンナノチューブ含有チタン合金の摺動特性と細胞適合性2013

    • Author(s)
      白坂和歌子、植月啓太、中村順一、佐粧孝久、高橋和久、鈴木昌彦
    • Journal Title

      臨床バイオメカニクス

      Volume: 34 Pages: 185-190

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] カーボンナノチューブ添加チタン合金の人工関節摺動面材料としての評価2013

    • Author(s)
      白坂和歌子、波多野創、植月啓太、西村直之、中村順一、佐粧孝久、高橋和久、鈴木昌彦
    • Organizer
      第28回日本整形外科学会基礎学術集会
    • Place of Presentation
      千葉市
    • Related Report
      2013 Research-status Report
  • [Presentation] 熱酸化Ti-15Zr-4Mb-4Ta合金はMC3T3-E1細胞のosteopontin分泌を促進する2013

    • Author(s)
      鯉沼縁、白坂和歌子、濱田雄平、山本知世、佐藤洋美、山浦克典、上野光一、鈴木昌彦
    • Organizer
      第35回日本バイオマテリアル学会
    • Place of Presentation
      東京都
    • Related Report
      2013 Research-status Report
  • [Presentation] CNT含有チタン合金の摺動特性2012

    • Author(s)
      白坂和歌子、原田賢二、綱嶋義貴、植月啓太、西村直之、中村順一、佐粧孝久、高橋和久 鈴木昌彦
    • Organizer
      第39回日本臨床バイオメカニクス学会
    • Place of Presentation
      千葉市
    • Related Report
      2012 Research-status Report

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Published: 2013-05-31   Modified: 2019-07-29  

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