| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
The purpose of this study is to prevent steroid-induced osteonecrosis of the femoral head (ONFH) by analyzing genetic polymorphism. First, we made a short list of candidate gene by primary screening with microarray. Then, we tried to detect the gene related with the steroid-induced ONFH by analyzing the base sequence of the candidate gene and analyze the single nucleotide polymorphism (SNPs) of the candidate gene. We detected the SNPs related with steroid-induced ONFH, and analyzed the association with each SNPs. However, we cannot detect the new SNPs related with steroid-induced ONFH.
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