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Non-invasive assessment of oxygen supply-demand balance with tissue spectroscopy.

Research Project

Project/Area Number 24592361
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionToho University

Principal Investigator

KOTAKE Yoshifumi  東邦大学, 医学部, 教授 (70195733)

Co-Investigator(Kenkyū-buntansha) OCHIAI Ryoichi  東邦大学, 医学部, 教授 (70146695)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Keywords多波長パルスオキシメトリー / 近赤外線組織スペクトロスコピー / 脈波 / 酸素需給バランス / 多波長パルスオキシメーター / スペクトロメトリー / 循環動態モニタ
Outline of Final Research Achievements

This project achieved following three major goals.
First, we evaluated the accuracy and feasibility of non-invasive, continuous monitoring of hemoglobin concentration based on pulseoximetric technology. We found the accuracy of such device failed to achieve required accuracy for immediate clinical application. Second, we compared central venous pressure (CVP) and respiratory variation of stroke volume (SVV) as an estimate of ventricular preload. We found SVV is closely correlated with ventricular preload than CVP. Third, we evaluated the relationship between mixed venous saturation and tissue oxygen saturation at thenar muscle. We found weak linear correlation between these two parameters.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (2 results)

All 2015 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 2 results)

  • [Journal Article] The comparison between stroke volume variation and filling pressure as an estimate of right ventricular preload in patients undergoing renal transplantation2015

    • Author(s)
      Toyoda D, Fukuda M, Iwasaki R, Terada T, Sato N, Ochiai R, Kotake y.
    • Journal Title

      Journal of Anesthesia

      Volume: 29 Issue: 1 Pages: 40-46

    • DOI

      10.1007/s00540-014-1870-2

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Evaluation of multiwave pulse total-hemoglobinometer during anesthesia2014

    • Author(s)
      Toyoda D, Yasumura R, Fukuda M, Ochiai R, Kotake Y
    • Journal Title

      Journal of Anesthesia

      Volume: 28 Issue: 3 Pages: 463-466

    • DOI

      10.1007/s00540-013-1730-5

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant

URL: 

Published: 2013-05-31   Modified: 2019-07-29  

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