| Project/Area Number |
24592367
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Kawasaki Medical School |
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Principal Investigator |
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| Research Collaborator |
HIRAO Yoichi
TSUJI Marina
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | 血圧測定 / モニター / ドップラー / 脈波伝搬時間 / 血圧 / 非侵襲的モニター / 生体情報監視装置 / 非侵襲モニター / 脈波伝搬速度 / ドップラー血流計 / 非侵襲的血圧計測 / 無侵襲動脈圧モニター / 超音波 |
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| Outline of Final Research Achievements |
We examined the validity of our pressure monitoring system by comparing PTT derived systolic blood pressure (Dopp_SBP) with invasive radial systolic arterial pressure (Inv_SBP) with calibration every 15 min in the ICU setting. Carotid arterial flow via an 8-MHz Doppler probe, ECG, and radial arterial pressure signals were transferred to a personal computer at a rate of 1 kHz and processed to calculate Dopp_SBP from PTT using our own formula.
Results & conclusions:Inv_SBP ranged from 213 to 82 mmHg, and Dopp_SBP from 185 to 71 mmHg. The Bland-Altman plot of the comparison between Inv_SBP and Dopp_SBP revealed limits of agreement of -20.1 to 17.7 mmHg (mean difference, -1.2 mmHg). There was a significant close linear correlation between Inv_SBP and Dopp_SBP (y=0.95x + 7.51, R2=0.84, p<0.0001).The results of the study show that our system is feasible for systolic blood pressure tracking over a longer interval if it is combined with intermittent calibration.
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