Functional analysis for the cytokines produced by ASC and ASC-induced restoration of erectile function.
| Project/Area Number |
24592423
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Etsu 聖マリアンナ医科大学, 医学系研究科, 講師 (40313134)
TAKAHASHI Masao 東京大学医学部附属病院, 循環器内科, 助教 (00447418)
NOMIYA Akira 東京大学医学部附属病院, 泌尿器外科学, 助教 (30372379)
HIRATA Yasunobu 東京大学医学部附属病院, 循環器内科, 准教授 (70167609)
新美 文彩 東京大学, 医学部附属病院, 助教 (00376451)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 脂肪幹細胞 / 勃起不全治療 / 海綿体再生 / アドレノメジュリン |
|---|
| Outline of Final Research Achievements |
The aim of this study is to explore a better treatment for ED, we examined whether combination of AM and angiopoietin-1 (Ang-1) was more effective to treat ED than treatment with AM alone or Ang-1 alone. We also compared the effect of the combination therapy with that of treatment with vascular endothelial growth factor-A (VEGF-A).
Combination therapy with AM and Ang-1 potently restored erectile function and normal morphology of the cavernous body compared with VEGF-A administration. This combination therapy will be useful to treat ED patients with a severely damaged cavernous body.
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Report
(4 results)
Research Products
(8 results)
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[Journal Article] Improvement of symptoms of aging in males by a preparation LEOPIN ROYAL containing aged garlic extract and other five of natural medicines - comparison with traditional herbal medicines (Kampo).2014
Author(s)
Nishimatsu H, Kitamura T, Yamada D, Nomiya A, Niimi A, Suzuki M, Fujimura T, Fukuhara H, Nakagawa T, Enomoto Y, Kume H, Igawa Y, Homma Y.
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Journal Title
Aging Male
Volume: 17
Issue: 2
Pages: 112-116
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Adrenomedullin and Angiopoietin-1 have a integrated restiration activity on Erectile Function in Diabetic Rats: Comparison with the Combination Therapy with Vascular Endothelial Growth Factor and Angiopoietin-12013
Author(s)
Nishimatsu, Hiroaki; Niimi, Aya; Suzuki, Etsu; Nomiya, Akira; Fukuhara, Hiroshi; Fujimura, Tetsuya; Suzuki, Motofumi; Nakagawa, Tohru; Enomoto, Yutaka; Kume, Haruki; Homma, Yukio;
Organizer
AUA2013
Place of Presentation
San Diego Convention Center
Related Report
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