Analysis of human endometrial epithelial cell dynamics during implantation
Project/Area Number |
24592484
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Obstetrics and gynecology
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Research Institution | Keio University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
MARUYAMA Tetsuo 慶應医義塾大学, 医学部, 講師 (10209702)
MASUDA Hirotaka 慶應医義塾大学, 医学部, 助教 (80317198)
|
Project Period (FY) |
2012-04-01 – 2015-03-31
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Project Status |
Completed (Fiscal Year 2014)
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Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 生殖医学 / 着床 / 細胞運動 / 細胞接着 / 子宮内膜上皮細胞 / グリコデリン |
Outline of Final Research Achievements |
Knowledge of human implantation mechanism is essential for assisted reproductive technology. It is known that human endometrial epithelial cells fall into apoptosis and disappear for embryo passing through. This study demonstrated that a number of human endometrial epithelial cells efferent move away from the center of embryo attachment, in association with cell apoptosis of small number of endometrial epithelial cells during implantation in vitro.
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Report
(4 results)
Research Products
(20 results)
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[Journal Article] Psychological adjustment and psychosocial stress among Japanese couples with a history of recurrent pregnancy loss2012
Author(s)
M.Kagami, T.Maruyama, T.Koizumi, K.Miyazaki, S.Nishikawa-Uchida, H.Oda, H.Uchida, D.Fujisawa, N.Ozawa, L.Schmidt, Y.Yoshimura
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Journal Title
Human Reproduction
Volume: 27
Issue: 3
Pages: 787-794
DOI
Related Report
Peer Reviewed
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